Targeting Polycomb systems to regulate gene expression: modifications to a complex story. - Test2 - elhamkhani - TriplyDB

Targeting Polycomb systems to regulate gene expression: modifications to a complex story.

Targeting Polycomb systems to regulate gene expression: modifications to a complex story.

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BMI1: A Biomarker of Hematologic Malignancies Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance.KDM2B Recruitment of the Polycomb Group Complex, PRC1.1, Requires Cooperation between PCGF1 and BCORL1 Associating cellular epigenetic models with human phenotypes An Hdac1/Rpd3-Poised Circuit Balances Continual Self-Renewal and Rapid Restriction of Developmental Potential during Asymmetric Stem Cell Division.Epigenetics in normal and malignant hematopoiesis: An overview and update 2017.EZH2-mediated epigenetic silencing of TIMP2 promotes ovarian cancer migration and invasion.Systematic discovery of novel eukaryotic transcriptional regulators using sequence homology independent prediction Epigenomic Regulation of Schwann Cell Reprogramming in Peripheral Nerve Injury.Live-cell single-molecule tracking reveals co-recognition of H3K27me3 and DNA targets polycomb Cbx7-PRC1 to chromatin.RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes.Three-Dimensional Genome Organization and Function in Drosophila.PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes.Polycomb Group Gene E(z) Is Required for Spermatogonial Dedifferentiation in Drosophila Adult Testis.H2A monoubiquitination in Arabidopsis thaliana is generally independent of LHP1 and PRC2 activity.Molecular characteristics of uterine sarcomas.Role of the Polycomb Repressive Complex 2 (PRC2) in Transcriptional Regulation and Cancer.Maintaining cell identity: PRC2-mediated regulation of transcription and cancer.H3K27 methylation: a promiscuous repressive chromatin mark.Roles of pRB in the Regulation of Nucleosome and Chromatin Structures.O-GlcNAcylation and chromatin remodeling in mammals: an up-to-date overview.The emerging field of epigenetics in neurodegeneration and neuroprotection.Dynamic chromatin technologies: from individual molecules to epigenomic regulation in cells.Novel orally bioavailable EZH1/2 dual inhibitors with greater antitumor efficacy than an EZH2 selective inhibitor.Arabidopsis transcriptional repressor VAL1 triggers Polycomb silencing at FLC during vernalization.Early transcriptional and epigenetic regulation of CD8+ T cell differentiation revealed by single-cell RNA sequencing.An RB-EZH2 Complex Mediates Silencing of Repetitive DNA Sequences.Xist RNA repeat E is essential for ASH2L recruitment to the inactive X and regulates histone modifications and escape gene expression.Retrotransposons Are the Major Contributors to the Expansion of the Drosophila ananassae Muller F Element.Expanding the molecular signature of ossifying fibromyxoid tumors with two novel gene fusions: CREBBP-BCORL1 and KDM2A-WWTR1.Producing GST-Cbx7 Fusion Proteins from Escherichia coli Heterochromatin Reduction Correlates with the Increase of the KDM4B and KDM6A Demethylases and the Expression of Pericentromeric DNA during the Acquisition of a Transformed Phenotype.The SET1 Complex Selects Actively Transcribed Target Genes via Multivalent Interaction with CpG Island Chromatin.Plant epigenomics-deciphering the mechanisms of epigenetic inheritance and plasticity in plants.Targeting MUC1-C suppresses polycomb repressive complex 1 in multiple myeloma.Comparative epigenomics in the Brassicaceae reveals two evolutionarily conserved modes of PRC2-mediated gene regulation.Denaturing CLIP, dCLIP, Pipeline Identifies Discrete RNA Footprints on Chromatin-Associated Proteins and Reveals that CBX7 Targets 3' UTRs to Regulate mRNA Expression.RNA polymerase II primes Polycomb-repressed developmental genes throughout terminal neuronal differentiation.Cis and trans determinants of epigenetic silencing by Polycomb repressive complex 2 in Arabidopsis.Sm-ChIPi: Single-Molecule Chromatin Immunoprecipitation Imaging.

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Targeting Polycomb systems to regulate gene expression: modifications to a complex story.

http://www.wikidata.org/entity/Q38595464

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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Targeting Polycomb systems to regulate gene expression: modifications to a complex story.

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Targeting Polycomb systems to regulate gene expression: modifications to a complex story.

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Targeting Polycomb systems to regulate gene expression: modifications to a complex story.

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Nature Reviews Molecular Cell Biology

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Targeting Polycomb systems to regulate gene expression: modifications to a complex story.

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P2093

Nathan R Rose

http://www.w3.org/2001/XMLSchema#string

Neil P Blackledge

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Robert J Klose

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P2860

Molecular architecture of human polycomb repressive complex 2

A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells

Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1

Polycomb PHF19 binds H3K36me3 and recruits PRC2 and demethylase NO66 to embryonic stem cell genes during differentiation

An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting

ATRX directs binding of PRC2 to Xist RNA and Polycomb targets

TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein

An AUTS2-Polycomb complex activates gene expression in the CNS.

PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes

RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3

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643-649

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scholarly article

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10.1038/NRM4067

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11

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16

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2015-09-30T00:00:00Z

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1038534622

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26420232

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5469428

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