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Progranulin Gene Therapy Improves Lysosomal Dysfunction and Microglial Pathology Associated with Frontotemporal Dementia and Neuronal Ceroid Lipofuscinosis.Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of C9ORF72-repeat induced toxicity.The lysosomal function of progranulin, a guardian against neurodegenerationEarly lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice
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description
2017 nî lūn-bûn
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2017年の論文
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
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name
Lysosomal processing of progranulin
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type
label
Lysosomal processing of progranulin
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prefLabel
Lysosomal processing of progranulin
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P2093
P2860
P921
P1476
Lysosomal processing of progranulin
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P2093
Daniel H Paushter
Lirong Sun
Tuancheng Feng
Xiaolai Zhou
P2860
P2888
P356
10.1186/S13024-017-0205-9
P577
2017-08-23T00:00:00Z
P6179
1091307441