Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B.
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NMR Fragment Screening Hit Induces Plasticity of BRD7/9 BromodomainsDiscovery and Optimization of a Selective Ligand for the Switch/Sucrose Nonfermenting-Related Bromodomains of Polybromo Protein-1 by the Use of Virtual Screening and Hydration AnalysisSensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibitionEpigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals.Chromatin Remodelers: From Function to Dysfunction.Structure-Based Identification of Inhibitory Fragments Targeting the p300/CBP-Associated Factor Bromodomain.Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia.Discovery of a PCAF Bromodomain Chemical Probe.Selective targeting of Bromodomains of the Bromodomain-PHD Fingers family impairs osteoclast differentiation.Progress in the Development of non-BET Bromodomain Chemical Probes.Selective targeting of epigenetic reader domains.Bromodomains in Protozoan Parasites: Evolution, Function, and Opportunities for Drug Development.Selectivity on-target of bromodomain chemical probes by structure-guided medicinal chemistry and chemical biology.Stereoselective Synthesis of Tetrahydroindolizines through the Catalytic Formation of Pyridinium Ylides from Diazo Compounds.Bromodomain inhibitors and cancer therapy: From structures to applications.Chemical probes and inhibitors of bromodomains outside the BET family.Targeting Ligandable Pockets on Plant Homeodomain (PHD) Zinc Finger Domains by a Fragment-Based Approach.Design and synthesis of potent and selective inhibitors of BRD7 and BRD9 bromodomainsA poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP(2), an atypical bromodomain† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc03115j.Discovery of a PCAF Bromodomain Chemical Probe
P2860
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P2860
Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Discovery and Characterization ...... Bromodomains BAZ2A and BAZ2B.
@en
type
label
Discovery and Characterization ...... Bromodomains BAZ2A and BAZ2B.
@en
prefLabel
Discovery and Characterization ...... Bromodomains BAZ2A and BAZ2B.
@en
P2093
P2860
P50
P1476
Discovery and Characterization ...... Bromodomains BAZ2A and BAZ2B.
@en
P2093
Carolyn Selenski
Catherine Rogers
Chun-Wa Chung
Cynthia Tallant
David Jung
Marcus Bantscheff
Martin Philpott
Matthew Lindon
Oleg Fedorov
Paola Grandi
P2860
P304
P356
10.1021/ACS.JMEDCHEM.5B00209
P407
P577
2015-03-23T00:00:00Z