A mechanism for the suppression of homologous recombination in G1 cells.
about
Writers, Readers, and Erasers of Histone Ubiquitylation in DNA Double-Strand Break RepairCustomizing the genome as therapy for the β-hemoglobinopathiesCellular response to DNA interstrand crosslinks: the Fanconi anemia pathwayInterplay between Fanconi anemia and homologous recombination pathways in genome integrityInteraction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2Controlling DNA-End Resection: An Emerging Task for Ubiquitin and SUMODNA Polymerase θ: A Unique Multifunctional End-Joining MachineCullin3-KLHL15 ubiquitin ligase mediates CtIP protein turnover to fine-tune DNA-end resectionA SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomesCancer-causing mutations in the tumor suppressor PALB2 reveal a novel cancer mechanism using a hidden nuclear export signal in the WD40 repeat motifCTCF facilitates DNA double-strand break repair by enhancing homologous recombination repair.USP13 regulates the RAP80-BRCA1 complex dependent DNA damage response.Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1.Non-Homologous End Joining and Homology Directed DNA Repair Frequency of Double-Stranded Breaks Introduced by Genome Editing Reagents.Functional interrogation of non-coding DNA through CRISPR genome editing.Gene Therapy: The View from NCATS.Loss of Nrf2 abrogates the protective effect of Keap1 downregulation in a preclinical model of cutaneous squamous cell carcinoma.Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle.A genome editing primer for the hematologistSharpening the ends for repair: mechanisms and regulation of DNA resection.Mechanism and regulation of DNA end resection in eukaryotesWhen Genome Maintenance Goes Badly Awry.PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line.A phosphorylation-deubiquitination cascade regulates the BRCA2-RAD51 axis in homologous recombination.A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation.In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration.Current Progress in Therapeutic Gene Editing for Monogenic DiseasesGenome-wide mapping of long-range contacts unveils clustering of DNA double-strand breaks at damaged active genes.Naturally Occurring Off-Switches for CRISPR-Cas9.PCNA-Ub polyubiquitination inhibits cell proliferation and induces cell-cycle checkpoints.Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate.Therapeutic genome engineering via CRISPR-Cas systems.Emerging new tools to study and treat muscle pathologies: genetics and molecular mechanisms underlying skeletal muscle development, regeneration, and disease.The democratization of gene editing: Insights from site-specific cleavage and double-strand break repair.Factors forming the BRCA1-A complex orchestrate BRCA1 recruitment to the sites of DNA damage.Distinct binding of BRCA2 BRC repeats to RAD51 generates differential DNA damage sensitivity.Hereditary breast and ovarian cancer: new genes in confined pathways.Emerging cellular and gene therapies for congenital anemias.The control of DNA repair by the cell cycle.Precision genome editing in the CRISPR era.
P2860
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P2860
A mechanism for the suppression of homologous recombination in G1 cells.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
A mechanism for the suppression of homologous recombination in G1 cells.
@en
type
label
A mechanism for the suppression of homologous recombination in G1 cells.
@en
prefLabel
A mechanism for the suppression of homologous recombination in G1 cells.
@en
P2093
P2860
P50
P356
P1433
P1476
A mechanism for the suppression of homologous recombination in G1 cells.
@en
P2093
Alana Sherker
Alexandre Orthwein
Daniel Durocher
Jayme Salsman
Jordan Pinder
Meagan Munro
Radoslav I Enchev
Sébastien Landry
P2860
P2888
P304
P356
10.1038/NATURE16142
P407
P577
2015-12-09T00:00:00Z
P6179
1052100896