Molecular basis underlying resistance to Mps1/TTK inhibitors.
about
Structural basis of reversine selectivity in inhibiting Mps1 more potently than aurora B kinaseTargeting oncogenic vulnerabilities in triple negative breast cancer: biological bases and ongoing clinical studies.Chromosome misalignments induce spindle-positioning defects.In silico analyses identify gene-sets, associated with clinical outcome in ovarian cancer: role of mitotic kinases.MPS1 kinase as a potential therapeutic target in medulloblastoma.APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability.Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures.Disruption of the anaphase-promoting complex confers resistance to TTK inhibitors in triple-negative breast cancer.Mps1/TTK: a novel target and biomarker for cancer.Mps1 inhibitors synergise with low doses of taxanes in promoting tumour cell death by enhancement of errors in cell division.Targeting the cell cycle in breast cancer: towards the next phaseReversine inhibits Colon Carcinoma Cell Migration by Targeting JNK1
P2860
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P2860
Molecular basis underlying resistance to Mps1/TTK inhibitors.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Molecular basis underlying resistance to Mps1/TTK inhibitors.
@en
type
label
Molecular basis underlying resistance to Mps1/TTK inhibitors.
@en
prefLabel
Molecular basis underlying resistance to Mps1/TTK inhibitors.
@en
P2860
P356
P1433
P1476
Molecular basis underlying resistance to Mps1/TTK inhibitors
@en
P2860
P2888
P304
P356
10.1038/ONC.2015.319
P407
P577
2015-09-14T00:00:00Z
P6179
1003119893