HIF2α-Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma. - Test2 - elhamkhani - TriplyDB

HIF2α-Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma.

HIF2α-Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma.

http://www.wikidata.org/entity/Q38892263

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Novel drugs that target the metabolic reprogramming in renal cell cancer Aberrant Lipid Metabolism Promotes Prostate Cancer: Role in Cell Survival under Hypoxia and Extracellular Vesicles Biogenesis Lipid metabolic reprogramming in cancer cells Oncogenes strike a balance between cellular growth and homeostasis Lipid Droplets: A Key Cellular Organelle Associated with Cancer Cell Survival under Normoxia and Hypoxia Englerin A induces an acute inflammatory response and reveals lipid metabolism and ER stress as targetable vulnerabilities in renal cell carcinoma HIF isoforms have divergent effects on invasion, metastasis, metabolism and formation of lipid droplets.Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration.CDCP1 cleavage is necessary for homodimerization-induced migration of triple-negative breast cancer.Loss of vhl in the zebrafish pronephros recapitulates early stages of human clear cell renal cell carcinoma.Phospholipase D1-regulated autophagy supplies free fatty acids to counter nutrient stress in cancer cells Loss of HSulf-1: The Missing Link between Autophagy and Lipid Droplets in Ovarian Cancer.Oxygen availability and metabolic adaptations.Recent advances in expanding the coverage of the lipidome.The size matters: regulation of lipid storage by lipid droplet dynamics.Understanding the Intersections between Metabolism and Cancer Biology.Lipid droplet functions beyond energy storage.Targeting ACLY sensitizes castration-resistant prostate cancer cells to AR antagonism by impinging on an ACLY-AMPK-AR feedback mechanism.Hydroxyl-HIF2-alpha is potential therapeutic target for renal cell carcinomas.Lipid droplets, potential biomarker and metabolic target in glioblastoma.HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism.Inhibition of intracellular lipolysis promotes human cancer cell adaptation to hypoxia.Low neighbor of Brca1 gene expression predicts poor clinical outcome and resistance of sunitinib in clear cell renal cell carcinoma.Isolation, phenotypic characterization and genome wide analysis of a Chlamydomonas reinhardtii strain naturally modified under laboratory conditions: towards enhanced microalgal biomass and lipid production for biofuels.SREBP-1c as a molecular bridge between lipogenesis and cell cycle progression of clear cell renal carcinoma.Data-Independent Acquisition-Based Quantitative Proteomic Analysis Reveals Potential Biomarkers of Kidney Cancer.Lipid Metabolism and Lipid Droplets in Pancreatic Cancer and Stellate Cells.Microscale Mass Spectrometry Analysis of Extracellular Metabolites in Live Multicellular Tumor Spheroids.Oxygen availability and metabolic reprogramming in cancer.IRE1α RNase-dependent lipid homeostasis promotes survival in Myc-transformed cancers.Lysophosphatidylcholine acyltransferase 2-mediated lipid droplet production supports colorectal cancer chemoresistance.Stress-responsive HILPDA is necessary for thermoregulation during fasting.A Late G1 Lipid Checkpoint That Is Dysregulated in Clear Cell Renal Carcinoma Cells.Hints on ATGL implications in cancer: beyond bioenergetic clues.Overexpression of PLIN2 is a prognostic marker and attenuates tumor progression in clear cell renal cell carcinoma.Abundance of TRAIL attenuated by HIF2α and c-FLIP affects malignancy in renal cell carcinomas.The proton pump inhibitor pantoprazole disrupts protein degradation systems and sensitizes cancer cells to death under various stresses.Hypoxia-Inducible Factor 2-Dependent Pathways Driving Von Hippel-Lindau-Deficient Renal Cancer.Plin4-Dependent Lipid Droplets Hamper Neuronal Mitophagy in the MPTP/p-Induced Mouse Model of Parkinson's Disease.PPARγ is dispensable for clear cell renal cell carcinoma progression.

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P2860

HIF2α-Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma.

http://www.wikidata.org/entity/Q38892263

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2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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HIF2α-Dependent Lipid Storage ...... ear-Cell Renal Cell Carcinoma.

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HIF2α-Dependent Lipid Storage ...... ear-Cell Renal Cell Carcinoma.

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HIF2α-Dependent Lipid Storage ...... ear-Cell Renal Cell Carcinoma.

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Cancer Discovery

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HIF2α-Dependent Lipid Storage ...... lear-Cell Renal Cell Carcinoma

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Alison Grazioli

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Bo Qiu

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Brian Keith

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Daniel Ackerman

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Danielle J Sanchez

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Ekaterina Bobrovnikova-Marjon

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J Alan Diehl

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Joshua D Ochocki

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M Celeste Simon

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P2860

The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule

HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression

Comprehensive molecular characterization of clear cell renal cell carcinoma.

Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3

The unfolded protein response: from stress pathway to homeostatic regulation

Activation of a metabolic gene regulatory network downstream of mTOR complex 1

Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.

Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets.

Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment

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endoplasmic reticulum

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4456212

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