mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway. - Test2 - elhamkhani - TriplyDB

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.

http://www.wikidata.org/entity/Q30425628

about

Nuclear envelope phosphatase 1-regulatory subunit 1 (formerly TMEM188) is the metazoan Spo7p ortholog and functions in the lipin activation pathway Milk is not just food but most likely a genetic transfection system activating mTORC1 signaling for postnatal growth Regulation of TOR by small GTPases High stearoyl-CoA desaturase 1 expression is associated with shorter survival in breast cancer patients mTOR signaling in growth control and disease Fundamentals of cancer metabolism Amino Acid Sensing by mTORC1: Intracellular Transporters Mark the Spot Sirolimus and Everolimus Pathway: Reviewing Candidate Genes Influencing Their Intracellular Effects Transcriptional regulation of hepatic lipogenesis Oncogenes strike a balance between cellular growth and homeostasis The neurology of mTOR Twists in views on RB functions in cellular signaling, metabolism and stem cells mTOR-dependent cell survival mechanisms Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling Energy metabolism in the liver mTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic Interventions mTORC1 signaling activates NRF1 to increase cellular proteasome levels Lipid biology of breast cancer Targeting autophagy for the treatment of liver diseases Phosphoinositides: Key modulators of energy metabolism Nutrient sensing, metabolism, and cell growth control New advances in molecular mechanisms and emerging therapeutic targets in alcoholic liver diseases The role of tumor suppressor p53 in the antioxidant defense and metabolism The expanding role of mTOR in cancer cell growth and proliferation Reinstating aberrant mTORC1 activity in Huntington's disease mice improves disease phenotypes.PGC-1/Spargel Counteracts High-Fat-Diet-Induced Obesity and Cardiac Lipotoxicity Downstream of TOR and Brummer ATGL Lipase.Judicious Toggling of mTOR Activity to Combat Insulin Resistance and Cancer: Current Evidence and Perspectives Left-right asymmetry in the light of TOR: An update on what we know so far mTOR signaling in tumorigenesis Excessive Leucine-mTORC1-Signalling of Cow Milk-Based Infant Formula: The Missing Link to Understand Early Childhood Obesity Where is mTOR and what is it doing there?Oligodendrocyte precursor cell-intrinsic effect of Rheb1 controls differentiation and mediates mTORC1-dependent myelination in brain Basal Autophagy and Feedback Activation of Akt Are Associated with Resistance to Metformin-Induced Inhibition of Hepatic Tumor Cell Growth Leucine signaling in the pathogenesis of type 2 diabetes and obesity Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations Sterol Regulatory Element-Binding Proteins (SREBP) signalling The Complex Roles of Mechanistic Target of Rapamycin in Adipocytes and Beyond.The Sweet Path to Metabolic Demise: Fructose and Lipid Synthesis Lipin-1 regulation of phospholipid synthesis maintains endoplasmic reticulum homeostasis and is critical for triple-negative breast cancer cell survival.Lipin1 Regulates Skeletal Muscle Differentiation through Extracellular Signal-regulated Kinase (ERK) Activation and Cyclin D Complex-regulated Cell Cycle Withdrawal.

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mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.

http://www.wikidata.org/entity/Q30425628

description

2011 nî lūn-bûn

@nan

2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.

@ast

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.

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type

label

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.

@ast

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.

@en

prefLabel

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.

@ast

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.

@en

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J.CELL.2011.06.034

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P1476

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.

@en

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Anne E Carmack

http://www.w3.org/2001/XMLSchema#string

Brian N Finck

http://www.w3.org/2001/XMLSchema#string

David A Guertin

http://www.w3.org/2001/XMLSchema#string

David M Sabatini

http://www.w3.org/2001/XMLSchema#string

Eric Balderas

http://www.w3.org/2001/XMLSchema#string

Katherine L Madden

http://www.w3.org/2001/XMLSchema#string

Seong A Kang

http://www.w3.org/2001/XMLSchema#string

Shomit S Sengupta

http://www.w3.org/2001/XMLSchema#string

Thurl E Harris

http://www.w3.org/2001/XMLSchema#string

Timothy R Peterson

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P2860

Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival

Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin.

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408-420

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10.1016/J.CELL.2011.06.034

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3

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146

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Anne E Carpenter

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2011-08-01T00:00:00Z

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51546877

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21816276

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3336367

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