CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation.
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CIP2A Promotes T-Cell Activation and Immune Response to Listeria monocytogenes InfectionCIP2A down regulation enhances the sensitivity of pancreatic cancer cells to gemcitabine.The Basic Biology of PP2A in Hematologic Cells and MalignanciesOverexpression of CIP2A is an independent prognostic indicator in nasopharyngeal carcinoma and its depletion suppresses cell proliferation and tumor growth.PP2A inhibition determines poor outcome and doxorubicin resistance in early breast cancer and its activation shows promising therapeutic effectsCellular localization of CIP2A determines its prognostic impact in superficial spreading and nodular melanoma.HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities.ATG16L1 phosphorylation is oppositely regulated by CSNK2/casein kinase 2 and PPP1/protein phosphatase 1 which determines the fate of cardiomyocytes during hypoxia/reoxygenation.CIP2A is a candidate therapeutic target in clinically challenging prostate cancer cell populations.AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation.Expression of cancerous inhibitor of protein phosphatase 2A in human triple negative breast cancer correlates with tumor survival, invasion and autophagy.Oncogenic nexus of cancerous inhibitor of protein phosphatase 2A (CIP2A): an oncoprotein with many hands.All roads lead to PP2A: exploiting the therapeutic potential of this phosphatase.Role of "oncogenic nexus" of CIP2A in breast oncogenesis: how does it work?Chaperone-mediated autophagy prevents cellular transformation by regulating MYC proteasomal degradation.MIR7-3HG, a MYC-dependent modulator of cell proliferation, inhibits autophagy by a regulatory loop involving AMBRA1.Cip2a promotes cell cycle progression in triple-negative breast cancer cells by regulating the expression and nuclear export of p27Kip1.Lyssavirus phosphoproteins increase mitochondrial complex I activity and levels of reactive oxygen species.Serine 62-Phosphorylated MYC Associates with Nuclear Lamins and Its Regulation by CIP2A Is Essential for Regenerative Proliferation.A reversible phospho-switch mediated by ULK1 regulates the activity of autophagy protease ATG4B.Metabolic Labeling with an Alkyne-modified Isoprenoid Analog Facilitates Imaging and Quantification of the Prenylome in Cells.PP2A mediates apoptosis or autophagic cell death in multiple myeloma cell lines.EBP50 suppresses the proliferation of MCF-7 human breast cancer cells via promoting Beclin-1/p62-mediated lysosomal degradation of c-Myc.TransCONFIRM: Identification of a Genetic Signature of Response to Fulvestrant in Advanced Hormone Receptor-Positive Breast Cancer.A large-scale RNA interference screen identifies genes that regulate autophagy at different stages.Oncoprotein CIP2A promotes the disassembly of primary cilia and inhibits glycolytic metabolism.
P2860
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P2860
CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation.
description
2014 nî lūn-bûn
@nan
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
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2014年论文
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2014年论文
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name
CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation.
@en
CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation.
@nl
type
label
CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation.
@en
CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation.
@nl
prefLabel
CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation.
@en
CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation.
@nl
P2093
P2860
P50
P356
P1476
CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation.
@en
P2093
Anna Rytter
Monika Mortensen
Pietri Puustinen
P2860
P304
P356
10.1083/JCB.201304012
P407
P577
2014-03-01T00:00:00Z