Structure of an archaeal PCNA1-PCNA2-FEN1 complex: elucidating PCNA subunit and client enzyme specificity - Test2 - elhamkhani - TriplyDB

Structure of an archaeal PCNA1-PCNA2-FEN1 complex: elucidating PCNA subunit and client enzyme specificity

Structure of an archaeal PCNA1-PCNA2-FEN1 complex: elucidating PCNA subunit and client enzyme specificity

http://www.wikidata.org/entity/Q39114197

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Okazaki fragment maturation: nucleases take centre stage DNA replication in the archaea The RFC clamp loader: structure and function Double strand binding-single strand incision mechanism for human flap endonuclease: implications for the superfamily Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening PCNA directs type 2 RNase H activity on DNA replication and repair substrates Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1 Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family Experimental phasing using zinc anomalous scattering The UmuC subunit of the E. coli DNA polymerase V shows a unique interaction with the β-clamp processivity factor Structure of monoubiquitinated PCNA: implications for DNA polymerase switching and Okazaki fragment maturation.A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp PCNA interacts with Prox1 and represses its transcriptional activity Vaccinia virus G8R protein: a structural ortholog of proliferating cell nuclear antigen (PCNA)Purification, crystallization and preliminary X-ray analysis of the PCNA2-PCNA3 complex from Sulfolobus tokodaii strain 7 PCNA and XPF cooperate to distort DNA substrates Modulation of the Pyrococcus abyssi NucS endonuclease activity by replication clamp at functional and structural levels.Characterization of the replication initiator Orc1/Cdc6 from the Archaeon Picrophilus torridus Fen1 mutations that specifically disrupt its interaction with PCNA cause aneuploidy-associated cancer Disruption of the FEN-1/PCNA interaction results in DNA replication defects, pulmonary hypoplasia, pancytopenia, and newborn lethality in mice.Deletion of dnaN1 generates a mutator phenotype in Bacillus anthracis.PCNA stimulates catalysis by structure-specific nucleases using two distinct mechanisms: substrate targeting and catalytic step.Sulfolobus chromatin proteins modulate strand displacement by DNA polymerase B1 Dynamics of enzymatic interactions during short flap human Okazaki fragment processing by two forms of human DNA polymerase δ.Recombinant production, crystallization and preliminary X-ray analysis of PCNA from the psychrophilic archaeon Methanococcoides burtonii DSM 6242.Expression, purification and preliminary X-ray analysis of proliferating cell nuclear antigen from the archaeon Thermococcus thioreducens.The role of the DNA sliding clamp in Okazaki fragment maturation in archaea and eukaryotes.Rapid progress of DNA replication studies in Archaea, the third domain of life.Regulation of human DNA polymerase delta in the cellular responses to DNA damage.Rings in the extreme: PCNA interactions and adaptations in the archaea.Structural studies of DNA end detection and resection in homologous recombination.Structural insights into the function of ZRANB3 in replication stress response.Proliferating cell nuclear antigen restores the enzymatic activity of a DNA ligase I deficient in DNA binding.Genetic technologies for extremely thermophilic microorganisms of Sulfolobus, the only genetically tractable genus of crenarchaea.Single-molecule characterization of Fen1 and Fen1/PCNA complexes acting on flap substrates Coordination of multiple enzyme activities by a single PCNA in archaeal Okazaki fragment maturation.Mutations in the Bacillus subtilis beta clamp that separate its roles in DNA replication from mismatch repair.Three proliferating cell nuclear antigen homologues from Metallosphaera sedula form a head-to-tail heterotrimer.Introduction of selective intersubunit disulfide bonds into self-assembly protein scaffold to enhance an artificial multienzyme complex's activity.The architecture of an Okazaki fragment-processing holoenzyme from the archaeon Sulfolobus solfataricus.

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P2860

Structure of an archaeal PCNA1-PCNA2-FEN1 complex: elucidating PCNA subunit and client enzyme specificity

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2006 nî lūn-bûn

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Structure of an archaeal PCNA1 ...... and client enzyme specificity

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Structure of an archaeal PCNA1 ...... and client enzyme specificity.

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Structure of an archaeal PCNA1 ...... and client enzyme specificity

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Structure of an archaeal PCNA1 ...... and client enzyme specificity.

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Structure of an archaeal PCNA1 ...... and client enzyme specificity

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Structure of an archaeal PCNA1 ...... and client enzyme specificity.

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Structure of an archaeal PCNA1 ...... and client enzyme specificity

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Mairi L Kilkenny

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S Mark Roe

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Sarah A Jones

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P2860

Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity

Human homologs of Schizosaccharomyces pombe rad1, hus1, and rad9 form a DNA damage-responsive protein complex

The human checkpoint sensor and alternative DNA clamp Rad9-Rad1-Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machinery

Human NTH1 physically interacts with p53 and proliferating cell nuclear antigen

Structural and biochemical studies of human proliferating cell nuclear antigen complexes provide a rationale for cyclin association and inhibitor design

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Building a replisome from interacting pieces: sliding clamp complexed to a peptide from DNA polymerase and a polymerase editing complex

Physical interaction between proliferating cell nuclear antigen and replication factor C from Pyrococcus furiosus

Three-dimensional structure of the beta subunit of E. coli DNA polymerase III holoenzyme: a sliding DNA clamp

Structural basis for recruitment of translesion DNA polymerase Pol IV/DinB to the -clamp

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