DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity. - Test2 - elhamkhani - TriplyDB

DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity.

DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity.

http://www.wikidata.org/entity/Q39116807

about

The 26S proteasome is a multifaceted target for anti-cancer therapies PICT-1 is a key nucleolar sensor in DNA damage response signaling that regulates apoptosis through the RPL11-MDM2-p53 pathway One-carbon metabolism and nucleotide biosynthesis as attractive targets for anticancer therapy.DNA damage modulates interactions between microRNAs and the 26S proteasome A novel DAG-dependent mechanism links PKCɑ and Cyclin B1 regulating cell cycle progression.Loss of urokinase receptor sensitizes cells to DNA damage and delays DNA repair The deubiquitinating enzyme USP17 is associated with non-small cell lung cancer (NSCLC) recurrence and metastasis.E3 ubiquitin ligase Pirh2 enhances tumorigenic properties of human non-small cell lung carcinoma cells.Polypharmacology of small molecules targeting the ubiquitin-proteasome and ubiquitin-like systems.KMT Set7/9 affects genotoxic stress response via the Mdm2 axis.UPS Activation in the Battle Against Aging and Aggregation-Related Diseases: An Extended Review.KMTase Set7/9 is a critical regulator of E2F1 activity upon genotoxic stress miR-16 and miR-26a target checkpoint kinases Wee1 and Chk1 in response to p53 activation by genotoxic stress.Proteasome expression and activity in cancer and cancer stem cells.Human EHMT2/G9a activates p53 through methylation-independent mechanism.Regulation of Endoribonuclease Activity of Alpha-Type Proteasome Subunits in Proerythroleukemia K562 Upon Hemin-Induced Differentiation.Loss of FBXO7 (PARK15) results in reduced proteasome activity and models a parkinsonism-like phenotype in mice Proteomic analysis of affinity-purified extracellular proteasomes reveals exclusively 20S complexes.Positioning of proteasome inhibitors in therapy of solid malignancies.No evidence for immunoproteasomes in chicken lymphoid organs and activated lymphocytes.Simultaneous EGFP and tag labeling of the β7 subunit for live imaging and affinity purification of functional human proteasomes.Extracellular Proteasomes Are Deficient in 19S Subunits as Revealed by iTRAQ Quantitative Proteomics.Expression and Clinical Role of Cdc5L as a Novel Cell Cycle Protein in Hepatocellular Carcinoma.

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P2860

DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity.

http://www.wikidata.org/entity/Q39116807

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

@zh-tw

2013年论文

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2013年论文

@zh

2013年论文

@zh-cn

name

DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity.

@en

DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity.

@nl

type

label

DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity.

@en

DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity.

@nl

prefLabel

DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity.

@en

DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity.

@nl

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ONCOTARGET.1060

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DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity.

@en

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Andrew Bottrill

http://www.w3.org/2001/XMLSchema#string

Gerry Melino

http://www.w3.org/2001/XMLSchema#string

Nickolai A Barlev

http://www.w3.org/2001/XMLSchema#string

Tatiana N Moiseeva

http://www.w3.org/2001/XMLSchema#string

P2860

Immunoaffinity profiling of tyrosine phosphorylation in cancer cells

A probability-based approach for high-throughput protein phosphorylation analysis and site localization

A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes

Mass spectrometric characterization of the affinity-purified human 26S proteasome complex

Large-scale characterization of HeLa cell nuclear phosphoproteins

Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

Mapping and structural dissection of human 20 S proteasome using proteomic approaches

UniProt: the Universal Protein knowledgebase

Systematic and quantitative assessment of the ubiquitin-modified proteome

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1338-1348

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scholarly article

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10.18632/ONCOTARGET.1060

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