DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity.
about
The 26S proteasome is a multifaceted target for anti-cancer therapiesPICT-1 is a key nucleolar sensor in DNA damage response signaling that regulates apoptosis through the RPL11-MDM2-p53 pathwayOne-carbon metabolism and nucleotide biosynthesis as attractive targets for anticancer therapy.DNA damage modulates interactions between microRNAs and the 26S proteasomeA novel DAG-dependent mechanism links PKCɑ and Cyclin B1 regulating cell cycle progression.Loss of urokinase receptor sensitizes cells to DNA damage and delays DNA repairThe deubiquitinating enzyme USP17 is associated with non-small cell lung cancer (NSCLC) recurrence and metastasis.E3 ubiquitin ligase Pirh2 enhances tumorigenic properties of human non-small cell lung carcinoma cells.Polypharmacology of small molecules targeting the ubiquitin-proteasome and ubiquitin-like systems.KMT Set7/9 affects genotoxic stress response via the Mdm2 axis.UPS Activation in the Battle Against Aging and Aggregation-Related Diseases: An Extended Review.KMTase Set7/9 is a critical regulator of E2F1 activity upon genotoxic stressmiR-16 and miR-26a target checkpoint kinases Wee1 and Chk1 in response to p53 activation by genotoxic stress.Proteasome expression and activity in cancer and cancer stem cells.Human EHMT2/G9a activates p53 through methylation-independent mechanism.Regulation of Endoribonuclease Activity of Alpha-Type Proteasome Subunits in Proerythroleukemia K562 Upon Hemin-Induced Differentiation.Loss of FBXO7 (PARK15) results in reduced proteasome activity and models a parkinsonism-like phenotype in miceProteomic analysis of affinity-purified extracellular proteasomes reveals exclusively 20S complexes.Positioning of proteasome inhibitors in therapy of solid malignancies.No evidence for immunoproteasomes in chicken lymphoid organs and activated lymphocytes.Simultaneous EGFP and tag labeling of the β7 subunit for live imaging and affinity purification of functional human proteasomes.Extracellular Proteasomes Are Deficient in 19S Subunits as Revealed by iTRAQ Quantitative Proteomics.Expression and Clinical Role of Cdc5L as a Novel Cell Cycle Protein in Hepatocellular Carcinoma.
P2860
Q26795764-5D058A3B-90E2-4631-8635-B60C30997B2EQ30090233-EAFB4297-0851-4019-AE65-3D41FE7B81EEQ33618935-A1CDFBA1-A760-45EC-BA9B-B92AD0FCEC9BQ33976943-9582C8FA-E33A-464E-BDCF-8C7747C6F830Q34956519-7626B569-2D66-4D72-B308-6414FB4F4E94Q35200009-45330B10-0022-4CFC-BF46-8ABF58AFBDF8Q37381637-98D18159-F241-49E3-B4B0-B96823CE682AQ37635616-42C0E3A9-7B11-4847-9673-4C8254291CFFQ38492748-FE73DA61-1AA0-43DF-8A32-E34E95BA7BC5Q38839983-88F0F6A5-0E0E-489D-9551-5FAFD2576769Q38950512-8C261AE8-6986-4CEB-A5B5-F63CDE9E653EQ38965954-FDF71354-239B-4DCA-BC21-A302EF82A7ACQ39043647-62B4022B-828B-4372-8CB8-3C88002C858BQ39201929-A2FDB367-0442-4ADE-A6FB-2B0996C6D5DFQ39565523-15B689AA-052A-4260-A5AF-54740756E6E6Q40218121-089E5955-DCA8-41F4-B075-8173C87560EBQ41730755-E53936BC-86F7-4BCB-9852-FA8B11AC4F5DQ47280042-5F97AD6D-E770-4C86-8B67-F5304CC2BD00Q47353792-72962629-1728-4564-8071-F81E8B519E5DQ48454630-649E1071-948C-4D7F-B1E1-B5976D72848AQ50450422-B98ECC25-CFA9-4129-B6A8-284DCAD2B15DQ51243625-ACFE424E-63FC-4D5B-BE54-1DA53CB8F566Q52903614-B79DC7A1-CAB9-4373-BFAB-61D3E682AE79
P2860
DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity.
@en
DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity.
@nl
type
label
DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity.
@en
DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity.
@nl
prefLabel
DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity.
@en
DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity.
@nl
P2093
P2860
P921
P356
P1433
P1476
DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity.
@en
P2093
Andrew Bottrill
Gerry Melino
Nickolai A Barlev
Tatiana N Moiseeva
P2860
P304
P356
10.18632/ONCOTARGET.1060
P407
P577
2013-09-01T00:00:00Z