A conserved proliferating cell nuclear antigen-interacting protein sequence in Chk1 is required for checkpoint function
about
The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stressDNA damage control: regulation and functions of checkpoint kinase 1Proliferating cell nuclear antigen is protected from degradation by forming a complex with MutT Homolog2Roles of Chk1 in cell biology and cancer therapyA chromatin-bound kinase, ERK8, protects genomic integrity by inhibiting HDM2-mediated degradation of the DNA clamp PCNA.The interaction between checkpoint kinase 1 (Chk1) and the minichromosome maintenance (MCM) complex is required for DNA damage-induced Chk1 phosphorylation.The fork and the kinase: a DNA replication tale from a CHK1 perspective.Phosphorylation of Minichromosome Maintenance 3 (MCM3) by Checkpoint Kinase 1 (Chk1) Negatively Regulates DNA Replication and Checkpoint Activation.Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA.Coupling cellular localization and function of checkpoint kinase 1 (Chk1) in checkpoints and cell viabilityA novel Chk1-binding peptide that enhances genotoxic sensitivity through the cellular redistribution of nuclear Chk1.Dual functions of DNA replication forks in checkpoint signaling and PCNA ubiquitinationTaking the time to make important decisions: the checkpoint effector kinases Chk1 and Chk2 and the DNA damage response.KA1-targeted regulatory domain mutations activate Chk1 in the absence of DNA damageChk1 Promotes DNA Damage Response Bypass following Oxidative Stress in a Model of Hydrogen Peroxide-Associated Ulcerative Colitis through JNK Inactivation and Chromatin Binding.Rapid and transient recruitment of DNMT1 to DNA double-strand breaks is mediated by its interaction with multiple components of the DNA damage response machinery.CRL4(CDT2) targets CHK1 for PCNA-independent destruction.Claspin and Chk1 regulate replication fork stability by different mechanisms.Intramolecular autoinhibition of checkpoint kinase 1 is mediated by conserved basic motifs of the C-terminal kinase-associated 1 domain.
P2860
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P2860
A conserved proliferating cell nuclear antigen-interacting protein sequence in Chk1 is required for checkpoint function
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A conserved proliferating cell ...... quired for checkpoint function
@en
A conserved proliferating cell ...... uired for checkpoint function.
@nl
type
label
A conserved proliferating cell ...... quired for checkpoint function
@en
A conserved proliferating cell ...... uired for checkpoint function.
@nl
prefLabel
A conserved proliferating cell ...... quired for checkpoint function
@en
A conserved proliferating cell ...... uired for checkpoint function.
@nl
P2093
P2860
P356
P1476
A conserved proliferating cell ...... quired for checkpoint function
@en
P2093
Clare H McGowan
David Gillespie
Jennifer Scorah
John R Yates
Mary Scott
Meng-Qiu Dong
P2860
P304
17250-17259
P356
10.1074/JBC.M800369200
P407
P577
2008-04-30T00:00:00Z