Cdc7-Dbf4 and the human S checkpoint response to UVC - Test2 - elhamkhani - TriplyDB

Cdc7-Dbf4 and the human S checkpoint response to UVC

Cdc7-Dbf4 and the human S checkpoint response to UVC

http://www.wikidata.org/entity/Q24672815

about

Saccharomyces cerevisiae Dbf4 Has Unique Fold Necessary for Interaction with Rad53 Kinase Titanium dioxide nanoparticles activate the ATM-Chk2 DNA damage response in human dermal fibroblasts.Global regulation of genome duplication in eukaryotes: an overview from the epifluorescence microscope.DNA damage response and tumorigenesis in Mcm2-deficient mice Chk1 promotes replication fork progression by controlling replication initiation.Replication licensing and the DNA damage checkpoint.The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control.Revised genetic requirements for the decatenation G2 checkpoint: the role of ATM.The fork and the kinase: a DNA replication tale from a CHK1 perspective.Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint.c-Jun N-terminal kinase-mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forks Checkpoint kinase 2 (Chk2) inhibits the activity of the Cdc45/MCM2-7/GINS (CMG) replicative helicase complex.Effective intra-S checkpoint responses to UVC in primary human melanocytes and melanoma cell lines Cdt1 and Cdc6 are destabilized by rereplication-induced DNA damage.Integrating S-phase checkpoint signaling with trans-lesion synthesis of bulky DNA adducts.Checkpoint-dependent regulation of origin firing and replication fork movement in response to DNA damage in fission yeast.Analysis of re-replication from deregulated origin licensing by DNA fiber spreading Replicating damaged DNA in eukaryotes.Checkpoint regulation of replication forks: global or local?Is activation of the intra-S checkpoint in human fibroblasts an important factor in protection against UV-induced mutagenesis?Development of DNA damage response signaling biomarkers using automated, quantitative image analysis.The human intra-S checkpoint response to UVC-induced DNA damage.The Intra-S Checkpoint Responses to DNA Damage.The essential kinase ATR: ensuring faithful duplication of a challenging genome.Impact of Age and Insulin-Like Growth Factor-1 on DNA Damage Responses in UV-Irradiated Human Skin.A conserved proliferating cell nuclear antigen-interacting protein sequence in Chk1 is required for checkpoint function Inhibition of DNA damage-induced apoptosis through Cdc7-mediated stabilization of Tob.Hypoxic activation of ATR and the suppression of the initiation of DNA replication through cdc6 degradation Cdc7-Dbf4 kinase overexpression in multiple cancers and tumor cell lines is correlated with p53 inactivation.ATR-dependent activation of p38 MAP kinase is responsible for apoptotic cell death in cells depleted of Cdc7.Cdc25A serine 123 phosphorylation couples centrosome duplication with DNA replication and regulates tumorigenesis.Tumour growth environment modulates Chk1 signalling pathways and Chk1 inhibitor sensitivity.Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation.Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1.Human papilloma virus type16 E6 deregulates CHK1 and sensitizes human fibroblasts to environmental carcinogens independently of its effect on p53.ATR kinase inhibition induces unscheduled origin firing through a Cdc7-dependent association between GINS and And-1.Chk1 and 14-3-3 proteins inhibit atypical E2Fs to prevent a permanent cell cycle arrest.

P2860

Q27675891-41A9CAEC-4DCB-4D53-9047-080E1AD1C7B2 Q30432008-CCBC2372-CB96-4742-B5E4-4CDB3B888782 Q33314935-2553BE6C-6B85-4DEF-B854-DBB4A1A7D675 Q33940639-32AD798A-41CA-4799-8870-08577B866F36 Q34136566-5371BEF0-55B6-4868-9A1D-516BF7EB35FA Q34547673-FDDADA84-9AF5-4007-BB6D-A4B4763A42C0 Q34911467-CCCF07AA-B0D4-4CD0-8B19-722C777B2ECE Q34987984-6609B8A1-CB1C-4E02-A29F-D4809D54CEBC Q35205026-B82E3270-996E-45F0-B8F3-92E654897F45 Q35709940-DD4BA2A8-043D-412E-8A2F-83E486880C8A Q35953858-D5D2B704-9769-4CCF-AC76-D201F7DF6C1C Q36170865-BB3EC577-FEC4-4907-87A8-5B928A8C0420 Q36556389-D02E4B27-A4E9-4D94-9C25-C4D79D41D0B6 Q36869434-6332FEF0-545D-4C4C-81CC-6519B90773F5 Q36891684-304ED16A-6DEE-4F31-AAF7-82BF8A70C85F Q37033647-883EDF19-41B6-4D68-B287-F6727E1B7EAE Q37041809-231BCF81-E51D-464C-893C-FB8227C744F6 Q37340387-5AE61CBE-0E65-4676-B86D-6B041BEE08CE Q37357566-801E2E1D-9B86-4C37-8AD1-B5AF0A5CB01F Q37530284-EF754D83-C634-4232-A3C7-BB256562176F Q37604397-025C4E97-F985-41B5-99F1-37BE4A9EBFE1 Q37606136-C22E34D0-2E78-4FAC-B1B7-C3542D978E37 Q37676255-F8AAC0CB-5360-418F-A760-69527A29789E Q38622938-ECEFCBFE-5AF4-4470-B640-3845DDA4455F Q38937094-2AD2D248-D5EE-4234-BA64-076FB4668D4B Q39142830-3C208072-8BB3-4872-AFE9-8FE201E46ED8 Q39259207-6D1BF0E2-74B3-4C80-8F4E-999A786D03D0 Q39425996-3FD5BC4A-D096-4734-A4BB-C510D9036A68 Q39949011-6B9DB994-B737-40B9-8DDF-62ADF9EF8CCD Q39961624-4C21BD26-ECA7-484F-A87C-E6513F3A404B Q41353630-EFD83E96-E3C7-4133-A207-488E985DDF53 Q41545189-827F3342-E9AD-46AC-BD6B-62DCAD18CC73 Q41792126-2BDD5A85-7A4D-4437-B4C1-51291E53B1F9 Q41809632-1EC8D156-ECD7-455E-82F9-868FD3F25A07 Q42425307-036FF2D5-1EE5-4BBB-B41A-FE84547D4A85 Q46751337-09FF4367-5CF0-4518-8551-4848B91C6447 Q48177734-13881527-509F-4EB9-993E-903798501C39

P2860

Cdc7-Dbf4 and the human S checkpoint response to UVC

http://www.wikidata.org/entity/Q24672815

description

2007 nî lūn-bûn

@nan

2007 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի մարտին հրատարակված գիտական հոդված

@hy

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

Cdc7-Dbf4 and the human S checkpoint response to UVC

@ast

Cdc7-Dbf4 and the human S checkpoint response to UVC

@en

Cdc7-Dbf4 and the human S checkpoint response to UVC

@nl

type

label

Cdc7-Dbf4 and the human S checkpoint response to UVC

@ast

Cdc7-Dbf4 and the human S checkpoint response to UVC

@en

Cdc7-Dbf4 and the human S checkpoint response to UVC

@nl

prefLabel

Cdc7-Dbf4 and the human S checkpoint response to UVC

@ast

Cdc7-Dbf4 and the human S checkpoint response to UVC

@en

Cdc7-Dbf4 and the human S checkpoint response to UVC

@nl

P1433

Q24672815-1F18A494-1938-472A-926E-44DFDD6087E7

P1476

Q24672815-DDE3FE5B-E2CB-4F7F-B810-DD71BB6FF4ED

P2093

Q24672815-2F726A47-31E3-4E6D-B641-0940F7D98C78

Q24672815-33113A4D-F5B9-4B90-B6E6-B84B8FD461C2

Q24672815-4A9BDC56-1A43-4294-8B21-5D142E6D4CB0

Q24672815-80CE3F13-3399-4F0C-A4D2-DDAFE580D2E5

Q24672815-C69A0D2D-52B7-4AE5-A2F7-ADFEF971598E

Q24672815-D4B2AD01-A0D7-4A8F-B37A-3A6A1F13C1EA

Q24672815-D861A5B8-5C44-461C-8BEE-29B844484605

P2860

Q24672815-006431E9-145E-4B6F-89B1-B12D6CCD6E3E

Q24672815-0352F98B-B6A0-419A-B19A-70BA70D11CD6

Q24672815-0B2AE688-CC51-4FE4-A2ED-73BFC71C2926

Q24672815-154081E4-B6CB-43A0-B7C1-8EF8BADCCBCF

Q24672815-1AF7E8B8-E381-4D7B-9EBE-34D0C5F5E03C

Q24672815-2075FF9F-A44E-4642-8B63-0BAB5AFA2ACE

Q24672815-216E62CD-8B5F-4919-AC8D-1610191E206C

Q24672815-22BA4D34-60C8-4AEF-AA8D-245EE5CCCEDE

Q24672815-243606AC-E366-47E6-B1E6-274508C1CFDE

Q24672815-29A5760B-FC1A-44B5-B459-8FA420D9D788

P304

Q24672815-BA81CC2B-513A-424C-B8F9-1FCA495102E7

P31

Q24672815-43F5FDE4-C18B-41A1-BA8A-C0E95C6FE607

P3181

Q24672815-F3852A4C-0075-4034-AB9E-369CEE9F4AEB

P356

Q24672815-53D26D3E-3336-4851-9181-9D753E2645F5

P407

Q24672815-7FF1294A-3FAA-4A3E-9EDD-E04EDE11ACDE

P433

Q24672815-46B8CE08-D031-40AF-A7EE-9C2D6B3B73A6

P478

Q24672815-AB231BEA-7778-40FB-BD8E-F64D99987DD8

P50

Q24672815-743424E0-C105-428C-ACF5-AE7E22059BB0

P577

Q24672815-EC0556B3-B61D-4E05-A30E-E4BDA24E3731

P5875

Q24672815-48434B9C-0AA1-4839-B57B-82A76A049603

P698

Q24672815-A1DA6705-DA52-44AC-8622-986C4D74C071

P921

Q24672815-6D8D7046-5E49-4813-89D7-51F323B2913D

P932

Q24672815-47CD1A74-F34B-4484-BF46-F8EFEE85658A

P3181

P356

P1433

Journal of Biological Chemistry

P1476

Cdc7-Dbf4 and the human S checkpoint response to UVC

@en

P2093

Alexandra N Heinloth

http://www.w3.org/2001/XMLSchema#string

Dennis A Simpson

http://www.w3.org/2001/XMLSchema#string

Keziban Unsal-Kaçmaz

http://www.w3.org/2001/XMLSchema#string

Marila Cordeiro-Stone

http://www.w3.org/2001/XMLSchema#string

Richard S Paules

http://www.w3.org/2001/XMLSchema#string

Timothy P Heffernan

http://www.w3.org/2001/XMLSchema#string

William K Kaufmann

http://www.w3.org/2001/XMLSchema#string

P2860

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

ATM-dependent phosphorylation of nibrin in response to radiation exposure

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint

MDC1 is a mediator of the mammalian DNA damage checkpoint

Coupling of human circadian and cell cycles by the timeless protein.

Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase

Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling

Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication

P304

9458-68

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

2836420

http://www.w3.org/2001/XMLSchema#string

P356

10.1074/JBC.M611292200

http://www.w3.org/2001/XMLSchema#string

P407

P433

13

http://www.w3.org/2001/XMLSchema#string

P478

282

http://www.w3.org/2001/XMLSchema#string

P50

P577

2007-03-30T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6527746

http://www.w3.org/2001/XMLSchema#string

P698

17276990

http://www.w3.org/2001/XMLSchema#string

P921

P932

1839878

http://www.w3.org/2001/XMLSchema#string