about
Genomic diversity of colorectal cancer: Changing landscape and emerging targetsThe value of genomics in dissecting the RAS-network and in guiding therapeutics for RAS-driven cancersMolecular therapeutics in pancreas cancerWhat links BRAF to the heart function? New insights from the cardiotoxicity of BRAF inhibitors in cancer treatmentHuman correlates of provocative questions in pancreatic pathologyIn situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12CTargeting the RAS oncogene.Personalized medicine in sporadic pancreatic cancer without homologous recombination-deficiency: are we any closer?The antitumor effects of geraniol: Modulation of cancer hallmark pathways (Review)RIG-like Helicase Regulation of Chitinase 3-like 1 Axis and Pulmonary MetastasisThe sirtuins promote Dishevelled-1 scaffolding of TIAM1, Rac activation and cell migrationProgress in Making Ras as a Druggable TargetStructure-based inhibition of protein-protein interactions.Nf1 loss and Ras hyperactivation in oligodendrocytes induce NOS-driven defects in myelin and vasculatureUsing high-throughput sequencing transcriptome data for INDEL detection: challenges for cancer drug discovery.Synbindin in extracellular signal-regulated protein kinase spatial regulation and gastric cancer aggressiveness.New option for the initial management of metastatic pancreatic cancer?Personalized oncology through integrative high-throughput sequencing: a pilot study.Direct Ras Inhibitors Identified from a Structurally Rigidified Bicyclic Peptide Library.Development of siRNA payloads to target KRAS-mutant cancer.Molecular docking studies of anti-cancerous candidates in Hippophae rhamnoides and Hippophae salicifoliaProspective Development of Small Molecule Targets to Oncogenic Ras ProteinsEffects of insulin on human pancreatic cancer progression modeled in vitroDecreased tumorigenesis in mice with a Kras point mutation at C118MicroRNAs 206 and 21 cooperate to promote RAS-extracellular signal-regulated kinase signaling by suppressing the translation of RASA1 and SPRED1Targeting mutant KRAS for anticancer therapeutics: a review of novel small molecule modulators.IL-1α expression in pancreatic ductal adenocarcinoma affects the tumor cell migration and is regulated by the p38MAPK signaling pathway.Mutant KRAS as a critical determinant of the therapeutic response of colorectal cancer.Down-Regulation of miR-129-5p and the let-7 Family in Neuroendocrine Tumors and Metastases Leads to Up-Regulation of Their Targets Egr1, G3bp1, Hmga2 and Bach1.Inhibition of Ras signaling by blocking Ras-effector interactions with cyclic peptidesLoss of RhoA Exacerbates, Rather Than Dampens, Oncogenic K-Ras Induced Lung Adenoma Formation in Mice.Genomic classification of the RAS network identifies a personalized treatment strategy for lung cancerFunctional signaling pathway analysis of lung adenocarcinomas identifies novel therapeutic targets for KRAS mutant tumors.8-Hydroxyquinoline-based inhibitors of the Rce1 protease disrupt Ras membrane localization in human cells.Unlocking Pandora's box: personalising cancer cell death in non-small cell lung cancer.Multivalent Small-Molecule Pan-RAS Inhibitors.Combined targeting of EGFR/HER promotes anti-tumor efficacy in subsets of KRAS mutant lung cancer resistant to single EGFR blockade.Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.Micro-RNA-155 is induced by K-Ras oncogenic signal and promotes ROS stress in pancreatic cancer.Roles of palmitoylation and the KIKK membrane-targeting motif in leukemogenesis by oncogenic KRAS4A
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Therapeutic strategies for targeting ras proteins.
@en
Therapeutic strategies for targeting ras proteins.
@nl
type
label
Therapeutic strategies for targeting ras proteins.
@en
Therapeutic strategies for targeting ras proteins.
@nl
prefLabel
Therapeutic strategies for targeting ras proteins.
@en
Therapeutic strategies for targeting ras proteins.
@nl
P2093
P2860
P356
P1433
P1476
Therapeutic strategies for targeting ras proteins.
@en
P2093
Frank McCormick
Megan Salt
Stephan Gysin
P2860
P304
P356
10.1177/1947601911412376
P577
2011-03-01T00:00:00Z