Inhibiting early-stage events in HIV-1 replication by small-molecule targeting of the HIV-1 capsid
about
Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication.A novel anti-HIV active integrase inhibitor with a favorable in vitro cytochrome P450 and uridine 5'-diphospho-glucuronosyltransferase metabolism profile.Microplate-based assay for identifying small molecules that bind a specific intersubunit interface within the assembled HIV-1 capsid.A Cell Internalizing Antibody Targeting Capsid Protein (p24) Inhibits the Replication of HIV-1 in T Cells Lines and PBMCs: A Proof of Concept Study.Identification of a small molecule HIV-1 inhibitor that targets the capsid hexamer.Discovery of a small-molecule antiviral targeting the HIV-1 matrix protein.HIV-1 Capsid Inhibitors as Antiretroviral AgentsEnhanced autointegration in hyperstable simian immunodeficiency virus capsid mutants blocked after reverse transcriptionHIV-1 uncoating: connection to nuclear entry and regulation by host proteins.Comparison of Biochemical Properties of HIV-1 and HIV-2 Capsid Proteins.Inhibition of HIV-1 Maturation via Small-Molecule Targeting of the Amino-Terminal Domain in the Viral Capsid Protein.A Triazinone Derivative Inhibits HIV-1 Replication by Interfering with Reverse Transcriptase Activity.The NTD-CTD intersubunit interface plays a critical role in assembly and stabilization of the HIV-1 capsid.Discovery and optimization of novel small-molecule HIV-1 entry inhibitors using field-based virtual screening and bioisosteric replacement.Structure-activity relationships of a novel capsid targeted inhibitor of HIV-1 replication.Human cytosolic extracts stabilize the HIV-1 coreInhibitors of the HIV-1 capsid, a target of opportunity.Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Non-dividing CellsExploring Modifications of an HIV-1 Capsid Inhibitor: Design, Synthesis, and Mechanism of Action
P2860
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P2860
Inhibiting early-stage events in HIV-1 replication by small-molecule targeting of the HIV-1 capsid
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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name
Inhibiting early-stage events ...... targeting of the HIV-1 capsid
@en
Inhibiting early-stage events ...... targeting of the HIV-1 capsid.
@nl
type
label
Inhibiting early-stage events ...... targeting of the HIV-1 capsid
@en
Inhibiting early-stage events ...... targeting of the HIV-1 capsid.
@nl
prefLabel
Inhibiting early-stage events ...... targeting of the HIV-1 capsid
@en
Inhibiting early-stage events ...... targeting of the HIV-1 capsid.
@nl
P2093
P2860
P356
P1433
P1476
Inhibiting early-stage events ...... targeting of the HIV-1 capsid
@en
P2093
Amos B Smith
Amy Princiotto
Arne Schön
David M Jones
Eric Stavale
Ernesto Freire
Fred C Krebs
Gokul Swaminathan
Isaac Zentner
P2860
P304
P356
10.1128/JVI.05006-11
P407
P577
2012-05-30T00:00:00Z