SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling
about
Molecular basis for specificity of the Met1-linked polyubiquitin signalThe linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death.MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death.Mechanisms of regulation and diversification of deubiquitylating enzyme function.CYLD, A20 and OTULIN deubiquitinases in NF-κB signaling and cell death: so similar, yet so different.Linear ubiquitin chains: enzymes, mechanisms and biologyDiverse ubiquitin linkages regulate RIP kinases-mediated inflammatory and cell death signaling.Limiting inflammation-the negative regulation of NF-κB and the NLRP3 inflammasome.The B-box module of CYLD is responsible for its intermolecular interaction and cytoplasmic localization.SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination.A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN.Deletion of Spata2 by CRISPR/Cas9n causes increased inhibin alpha expression and attenuated fertility in male mice.SPATA2: more than a missing link.Determinants of E2-ubiquitin conjugate recognition by RBR E3 ligases.CRISPR whole-genome screening identifies new necroptosis regulators and RIPK1 alternative splicing.Necroptosis in development and diseases.Role of the NFκB-signaling pathway in cancer.The deubiquitinase MYSM1 dampens NOD2-mediated inflammation and tissue damage by inactivating the RIP2 complex
P2860
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P2860
SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling
@en
SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.
@nl
type
label
SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling
@en
SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.
@nl
prefLabel
SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling
@en
SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.
@nl
P2093
P2860
P50
P921
P1433
P1476
SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling
@en
P2093
Berthe K Fiil
David Komander
Derek Leske
Jane Wagstaff
Katrin Bagola
Mads Gyrd-Hansen
Stefan M V Freund
P2860
P304
P356
10.1016/J.MOLCEL.2016.08.001
P50
P577
2016-08-27T00:00:00Z