Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines.
about
The C-kit receptor-mediated signal transduction and tumor-related diseasesExploring the Dynamics of Propeller Loops in Human Telomeric DNA Quadruplexes Using Atomistic Simulations.Synthesis of bis-indole carboxamides as G-quadruplex stabilizing and inducing ligands.Targeting DNA G-quadruplexes with helical small molecules.Elevated levels of G-quadruplex formation in human stomach and liver cancer tissues.A Personal History of Quadruplex-Small Molecule Targeting.Screening of candidate G-quadruplex ligands for the human c-KIT promotorial region and their effects in multiple in-vitro models.Extended molecular dynamics of a c-kit promoter quadruplex.Ruthenium Complex "Light Switches" that are Selective for Different G-Quadruplex Structures.Mechanism of the antiproliferative activity of some naphthalene diimide G-quadruplex ligands.Design, synthesis, and biological evaluation of indenoisoquinoline rexinoids with chemopreventive potentialPyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cellsG-quadruplex interacting small molecules and drugs: from bench toward bedside.Synthesis and Evaluation of Quinazolone Derivatives as a New Class of c-KIT G-Quadruplex Binding Ligands.Flexibility and structural conservation in a c-KIT G-quadruplex.G-quadruplex-binding benzo[a]phenoxazines down-regulate c-KIT expression in human gastric carcinoma cells.A platinum(II) phenylphenanthroimidazole with an extended side-chain exhibits slow dissociation from a c-Kit G-quadruplex motif.Multivalent Interactions between an Aromatic Helical Foldamer and a DNA G-Quadruplex in the Solid State.Double stranded promoter region of BRAF undergoes to structural rearrangement in nearly physiological conditions.
P2860
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P2860
Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines.
description
2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
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2010年學術文章
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2010年學術文章
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name
Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines.
@en
Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines.
@nl
type
label
Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines.
@en
Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines.
@nl
prefLabel
Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines.
@en
Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines.
@nl
P2093
P2860
P356
P1476
Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines.
@en
P2093
Deborah A Sanders
Jonathan A Fletcher
Mallesham Bejugam
Mekala Gunaratnam
Shankar Balasubramanian
Stephen Neidle
P2860
P304
P356
10.1021/ML100062Z
P577
2010-07-01T00:00:00Z