Design, synthesis and evaluation of monovalent Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP.
about
The structure of XIAP BIR2: understanding the selectivity of the BIR domainsExpedient synthesis of highly potent antagonists of inhibitor of apoptosis proteins (IAPs) with unique selectivity for ML-IAPInducing death in tumor cells: roles of the inhibitor of apoptosis proteins.Characterization of Potent SMAC Mimetics that Sensitize Cancer Cells to TNF Family-Induced ApoptosisSmall-molecule IAP antagonists sensitize cancer cells to TRAIL-induced apoptosis: roles of XIAP and cIAPs.X-linked inhibitor of apoptosis protein - a critical death resistance regulator and therapeutic target for personalized cancer therapy.Design, synthesis and evaluation of inhibitor of apoptosis protein (IAP) antagonists that are highly selective for the BIR2 domain of XIAP.Investigating isoquinoline derivatives for inhibition of inhibitor of apoptosis proteins for ovarian cancer treatmentTargeting the intrinsic apoptosis pathway as a strategy for melanoma therapy.A critical role for cellular inhibitor of protein 2 (cIAP2) in colitis-associated colorectal cancer and intestinal homeostasis mediated by the inflammasome and survival pathways.
P2860
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P2860
Design, synthesis and evaluation of monovalent Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Design, synthesis and evaluati ...... e anti-apoptotic protein XIAP.
@en
Design, synthesis and evaluati ...... e anti-apoptotic protein XIAP.
@nl
type
label
Design, synthesis and evaluati ...... e anti-apoptotic protein XIAP.
@en
Design, synthesis and evaluati ...... e anti-apoptotic protein XIAP.
@nl
prefLabel
Design, synthesis and evaluati ...... e anti-apoptotic protein XIAP.
@en
Design, synthesis and evaluati ...... e anti-apoptotic protein XIAP.
@nl
P2093
P2860
P1476
Design, synthesis and evaluati ...... he anti-apoptotic protein XIAP
@en
P2093
Darren Finlay
Hongbin Yuan
John C Reed
Kate Welsh
Kristiina Vuori
Marcos González-López
Nicholas D P Cosford
Peter Teriete
Robert J Ardecky
Santhi Reddy Ganji
P2860
P304
P356
10.1016/J.BMCL.2011.05.049
P407
P577
2011-05-24T00:00:00Z