about
SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP)Mature DIABLO/Smac is produced by the IMP protease complex on the mitochondrial inner membraneXIAP: cell death regulation meets copper homeostasisA novel role for XIAP in copper homeostasis through regulation of MURR1Identification of a novel protein kinase Cδ-Smac complex that dissociates during paclitaxel-induced cell deathNo death without life: vital functions of apoptotic effectorsStructural classification of zinc fingers: survey and summary.Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs.Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosisOmi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosisThe anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sitesSMAC is expressed de novo in a subset of cervical cancer tumorsTargeting Cell Survival Proteins for Cancer Cell DeathResearch Advances on Pathways of Nickel-Induced ApoptosisNovel strategies to target the ubiquitin proteasome system in multiple myelomaUbiquitin-Mediated Regulation of Cell Death, Inflammation, and Defense of HomeostasisRegulation of Cell Death by IAPs and Their AntagonistsFine-tuning multiprotein complexes using small moleculesInhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammationSmall-molecule SMAC mimetics as new cancer therapeuticsConservation of hearing and protection of hair cells in cochlear implant patients' with residual hearingTargeting the apoptosis pathway in hematologic malignanciesMolecular mechanism of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitinationXIAP Induces NF-κB Activation via the BIR1/TAB1 Interaction and BIR1 DimerizationCrystal Structure of the BIR1 Domain of XIAP in Two Crystal FormsInteraction of a Cyclic, Bivalent Smac Mimetic with the X-Linked Inhibitor of Apoptosis Protein † ‡Structure-Based Design, Synthesis, Evaluation, and Crystallographic Studies of Conformationally Constrained Smac Mimetics as Inhibitors of the X-linked Inhibitor of Apoptosis Protein (XIAP) †Structural mechanisms of DIAP1 auto-inhibition and DIAP1-mediated inhibition of drICEStructural Insight into Inhibitor of Apoptosis Proteins Recognition by a Potent Divalent Smac-MimeticAntagonists induce a conformational change in cIAP1 that promotes autoubiquitinationStructural Basis for Recognition of H3T3ph and Smac/DIABLO N-terminal Peptides by Human SurvivinThe structure of XIAP BIR2: understanding the selectivity of the BIR domainsMotif mediated protein-protein interactions as drug targetsPutting the pieces together: How is the mitochondrial pathway of apoptosis regulated in cancer and chemotherapy?Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosisThe polypeptide chain-releasing factor GSPT1/eRF3 is proteolytically processed into an IAP-binding proteinA novel ubiquitin fusion system bypasses the mitochondria and generates biologically active Smac/DIABLOEndogenous association of TRAF2, TRAF3, cIAP1, and Smac with lymphotoxin beta receptor reveals a novel mechanism of apoptosisThe serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activityEctopic expression of new alternative splice variant of Smac/DIABLO increases mammospheres formation
P2860
Q24292189-CD1B9E9C-EB57-4437-A8AF-736D12EE176BQ24299687-18F1C85B-8ABE-4AFA-A90D-151CB995C4F7Q24300814-9B6D033F-07F2-4F8D-846A-E8A0945B379DQ24302274-688035CE-D2DE-4574-9330-3EAC60FE71B5Q24310544-60C22C42-6188-42F3-8F46-38B3BC204481Q24319057-8B37E59E-2FBB-43C9-9144-84792AAAF417Q24540502-48675701-0259-4103-B005-0D5C1195672DQ24544173-99A78EF1-0A33-4CF2-8203-20CDA8BCE67CQ24609324-4A81C3B6-E85B-4E86-9EFC-9B33A5C971C6Q24672350-4A3310DF-7D64-4A58-AE53-8D4306C12BFDQ24673550-5E1495CF-6322-4321-A7D8-5F137A5AEEDAQ24804096-8C251607-48FA-4B9E-A03E-CF4BE08B1960Q26765447-7BC3F058-725C-4EB6-85A2-3DC2E53FA610Q26772023-E7FB7094-A444-4268-8B41-7F5F613242A7Q26773246-E5F5EFB5-F8AC-4019-BE26-49BFAEE7A6B2Q26782575-398CE335-1099-46EF-92F3-B5360A5F5F37Q26782579-19942956-8CE9-4116-8DA9-2E46D632DBD7Q26822675-25342D87-700E-48D4-BA16-23C4A5B513ECQ26824586-42B5A410-C8CE-42A9-A0D0-7228B298072FQ26864204-AD2534D8-F118-4573-8FBF-F4DD73B5D50BQ27014934-4E524995-AE51-4298-8A9B-53A980AAAF4AQ27024422-E704FE59-5549-446E-A25F-36AF61D39B07Q27642254-E6549AE7-745E-4AF6-9CA0-A90B123FE58BQ27645534-97652856-DB83-4F1B-BBC1-5F5D229797B7Q27647264-A848D1E3-8A29-42BF-ABC2-66018B8A26A7Q27651733-9DE77FA4-63B8-4779-82C5-CA4ADE045F2DQ27652682-B6B57C1F-1B42-44E3-9C50-779E99773FC7Q27671407-5C39B710-46F6-4C82-822C-926F81C783C3Q27675179-6A18027B-0067-4152-A826-5839E5C5067DQ27675192-1C1F831C-4D93-46BF-9DC6-1D495AA5E065Q27676734-4D0E4EF9-4B2D-46E0-AC72-DE32AE1FF386Q27679855-0545FCF9-121F-4C2E-90BF-69B1BCEF7B5FQ28079554-7B9F6075-0B31-4E2D-931F-A3BD86E4D665Q28085240-23CB1AD8-8342-4F65-AF03-E445C7C0D5F7Q28186614-9AA5CE56-8B60-40AE-906F-D90DB7912282Q28187577-963B8A80-C681-414F-9976-AB425DD73668Q28201640-581A43F0-851B-441D-93CD-19B89499F333Q28207830-8640D45E-FBFE-4A54-A1D1-13430E662651Q28216093-A47571B0-6257-43B7-8ABD-045EF6870CCBQ28250105-BC8EB342-5835-4E8D-A049-60D329289476
P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Structural basis of IAP recognition by Smac/DIABLO
@ast
Structural basis of IAP recognition by Smac/DIABLO
@en
Structural basis of IAP recognition by Smac/DIABLO
@nl
type
label
Structural basis of IAP recognition by Smac/DIABLO
@ast
Structural basis of IAP recognition by Smac/DIABLO
@en
Structural basis of IAP recognition by Smac/DIABLO
@nl
prefLabel
Structural basis of IAP recognition by Smac/DIABLO
@ast
Structural basis of IAP recognition by Smac/DIABLO
@en
Structural basis of IAP recognition by Smac/DIABLO
@nl
P2093
P3181
P356
P1433
P1476
Structural basis of IAP recognition by Smac/DIABLO
@en
P2093
P2888
P304
P3181
P356
10.1038/35050012
P407
P577
2000-12-01T00:00:00Z
P6179
1013741960