RAD18 promotes DNA double-strand break repair during G1 phase through chromatin retention of 53BP1. - Test2 - elhamkhani - TriplyDB

RAD18 promotes DNA double-strand break repair during G1 phase through chromatin retention of 53BP1.

RAD18 promotes DNA double-strand break repair during G1 phase through chromatin retention of 53BP1.

http://www.wikidata.org/entity/Q39882034

about

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications PUB-NChIP--"in vivo biotinylation" approach to study chromatin in proximity to a protein of interest BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair Human RAD18 interacts with ubiquitylated chromatin components and facilitates RAD9 recruitment to DNA double strand breaks Systematic E2 screening reveals a UBE2D-RNF138-CtIP axis promoting DNA repair Msl2 is a novel component of the vertebrate DNA damage response 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair.Comparative analysis of zinc finger proteins involved in plant disease resistance The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI RAD18 activates the G2/M checkpoint through DNA damage signaling to maintain genome integrity after ionizing radiation exposure.Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1.Meiotic functions of RAD18.c-Jun N-terminal kinase-mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forks RNF168 forms a functional complex with RAD6 during the DNA damage response Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA.RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks.Eukaryotic DNA damage checkpoint activation in response to double-strand breaks.Rad18 and Rnf8 facilitate homologous recombination by two distinct mechanisms, promoting Rad51 focus formation and suppressing the toxic effect of nonhomologous end joining.Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway activation and cell survival following DNA Topoisomerase 1 inhibition.Reading chromatin signatures after DNA double-strand breaks.Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18.Recruitment of lysine demethylase 2A to DNA double strand breaks and its interaction with 53BP1 ensures genome stability.Tumor suppressor miR-145 reverses drug resistance by directly targeting DNA damage-related gene RAD18 in colorectal cancer.

P2860

Q24608343-0B7A6DCD-ACFE-4308-9D0C-0704AC0A902C Q24628756-41B27C1B-AF7B-4F3E-AD00-39A7D47E95C0 Q24632998-C1206AB6-94C4-4B9B-962B-2D454CF63783 Q27325197-DFA3615B-8884-4D91-A975-D9F90C58798E Q28115456-3530C07A-7A1C-4245-83FE-0C072D8B12F0 Q28534565-2A61BFAC-52F2-485C-9C92-1CBB1E4F4594 Q29465538-8DEA3879-8434-4A20-9158-08462285A12E Q34290557-17E4242C-8373-4F02-86F9-CBA9C3ACDE1B Q34390897-175AF70E-4915-483D-A366-5C3CE32C27BF Q35029423-CB53C14B-A6FD-4769-AE23-867EB5522CA2 Q35078454-D0CEBA25-E5DA-4A72-A093-75003A928FAE Q35125130-C5A8DC8C-0CBB-42EA-831B-14ABE27FFD5E Q35541520-5D414581-9AA6-46FB-83B1-A82785D85D61 Q35953858-26A792C9-A5F2-43DA-8E83-7B019899154C Q36882870-663A8B81-E4A9-4B43-A03F-B0048C82111B Q37396238-F831FF6E-3084-4DF4-A917-7D23AE8C13FF Q37421389-7BA95992-CDD2-419A-ABE5-639A4C740735 Q37956184-B6EC7CF4-3B1F-46FC-BC50-035F9393440B Q38938428-975F8D99-7C21-49DE-B987-FA3317300675 Q39561547-1A7DFDAC-D4AE-408E-A908-F64F8E8AA687 Q50494189-A8C2DDCD-9613-4B65-AFF2-6352A1800B2D Q51000552-BCF2E9F3-DDEB-4CBC-954A-296C8FD564A4 Q52691364-50C4727C-84C8-4D06-831B-67BE5381F020 Q53529113-C0CDDF37-F967-4FB9-9E63-5089DB731503

P2860

RAD18 promotes DNA double-strand break repair during G1 phase through chromatin retention of 53BP1.

http://www.wikidata.org/entity/Q39882034

description

2009 nî lūn-bûn

@nan

2009年の論文

@ja

2009年学术文章

@wuu

2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

2009年學術文章

@zh

2009年學術文章

@zh-hant

name

RAD18 promotes DNA double-stra ...... chromatin retention of 53BP1.

@en

RAD18 promotes DNA double-stra ...... chromatin retention of 53BP1.

@nl

type

label

RAD18 promotes DNA double-stra ...... chromatin retention of 53BP1.

@en

RAD18 promotes DNA double-stra ...... chromatin retention of 53BP1.

@nl

prefLabel

RAD18 promotes DNA double-stra ...... chromatin retention of 53BP1.

@en

RAD18 promotes DNA double-stra ...... chromatin retention of 53BP1.

@nl

P1433

Q39882034-965B82C3-95D0-443D-A04E-7DF4DAAD59CB

P1476

Q39882034-61891D89-B020-4D2C-A899-C4D8753FCA35

P2093

Q39882034-308A0773-CBA0-4CCC-9B6A-496B5DDC38A0

Q39882034-31CC563D-D568-409F-A48D-8E2BDEC211B0

Q39882034-33FBFF54-23F1-447C-A2F9-6E3271808D3B

Q39882034-45348E6A-7CA9-47C9-8728-0F2D78297C12

Q39882034-4B437527-3905-409D-8A1A-AB4B690E3973

Q39882034-7B188ED8-E686-426E-B298-AEF47C94A2D5

Q39882034-8C8F3CF7-6FFE-4AEB-8E40-92CA0B1C2609

Q39882034-99B9865A-6653-468D-A833-3568BDBB46B8

Q39882034-AB657FB1-6933-43F0-8186-F6260DF7618C

Q39882034-EB3C03F7-6A68-46FF-B158-4FA127FBADC9

P2860

Q39882034-007F3F41-32E3-4880-B1C0-1F993BA229A5

Q39882034-01A98EE4-ADD7-4C40-99ED-5E9A1F8060C7

Q39882034-0393E055-ADAB-4FCB-9BEF-51A6110A88B1

Q39882034-08A6E3D2-91A8-4058-863B-0C6722E32BBB

Q39882034-0D498D71-EBD6-449A-A3E9-509AF75CBC0A

Q39882034-1458F2F4-EC84-4AF9-831C-E66F51E8B0DF

Q39882034-2ADA75EB-A8B1-43A0-9FE3-D0AA3FF0FC06

Q39882034-2CF163F2-F520-48B8-91FA-50D82020DCD1

Q39882034-3A6E86DF-D183-4037-A0B4-9DD1A93A8862

Q39882034-3B20E6F5-585D-43EC-925C-F34A10FFC25F

P304

Q39882034-AA75FB6C-AEF3-41E4-AF3F-EEFB185A53A4

P31

Q39882034-29D75E73-3A62-4090-9AB1-9C2F12D1AC84

P356

Q39882034-24B0B8E9-DBAA-4566-89BA-23900FF6799F

P433

Q39882034-72458292-1B68-4D8C-9C7E-43BA46A008A6

P478

Q39882034-8D6A6094-2D3C-4E75-9BF7-5F868C18BE54

P577

Q39882034-4AEF2F9B-EBAF-4F6B-9A48-A4F397C807DB

P5875

Q39882034-A0685FF2-0781-44A0-86E0-CE1D5F52C730

P698

Q39882034-C0BD006B-8963-4D22-806B-641BA64E7097

P932

Q39882034-DDA13C29-075B-4BBC-B614-C3778E08B839

P356

P1433

Nucleic Acids Research

P1476

RAD18 promotes DNA double-stra ...... chromatin retention of 53BP1.

@en

P2093

Jinghua Sun

http://www.w3.org/2001/XMLSchema#string

Kazuaki Tokunaga

http://www.w3.org/2001/XMLSchema#string

Kenji Watanabe

http://www.w3.org/2001/XMLSchema#string

Kuniyoshi Iwabuchi

http://www.w3.org/2001/XMLSchema#string

Masaru Yamaizumi

http://www.w3.org/2001/XMLSchema#string

Mitsumasa Hashimoto

http://www.w3.org/2001/XMLSchema#string

Satoshi Tateishi

http://www.w3.org/2001/XMLSchema#string

Takayasu Date

http://www.w3.org/2001/XMLSchema#string

Tokio Tani

http://www.w3.org/2001/XMLSchema#string

Yuri Tsuji

http://www.w3.org/2001/XMLSchema#string

P2860

Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens

A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response

MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks

Rad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrest

Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination

Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

P304

2176-2193

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1093/NAR/GKP082

http://www.w3.org/2001/XMLSchema#string

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

37

http://www.w3.org/2001/XMLSchema#string

P577

2009-02-19T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

24026603

http://www.w3.org/2001/XMLSchema#string

P698

19228710

http://www.w3.org/2001/XMLSchema#string

P932

2673428

http://www.w3.org/2001/XMLSchema#string