Alterations in cellular metabolism triggered by URA7 or GLN3 inactivation cause imbalanced dNTP pools and increased mutagenesis.

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DNA replication and mismatch repair safeguard against metabolic imbalances.Fast and sensitive HPLC-MS/MS method for direct quantification of intracellular deoxyribonucleoside triphosphates from tissue and cells.

P2860

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P2860

Alterations in cellular metabolism triggered by URA7 or GLN3 inactivation cause imbalanced dNTP pools and increased mutagenesis.

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http://www.wikidata.org/entity/Q40248007

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

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2017年論文

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2017年論文

@zh-hk

2017年論文

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2017年論文

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2017年论文

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2017年论文

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2017年论文

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Alterations in cellular metabo ...... ols and increased mutagenesis.

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type

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Alterations in cellular metabo ...... ols and increased mutagenesis.

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prefLabel

Alterations in cellular metabo ...... ols and increased mutagenesis.

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P1476

Alterations in cellular metabo ...... ols and increased mutagenesis.

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P2093

Cemile Ümran Ceylan

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Gloria Reyes

http://www.w3.org/2001/XMLSchema#string

Kerstin Gries

http://www.w3.org/2001/XMLSchema#string

Matthias Meurer

http://www.w3.org/2001/XMLSchema#string

Michael Knop

http://www.w3.org/2001/XMLSchema#string

Sushma Sharma

http://www.w3.org/2001/XMLSchema#string

Tobias T Schmidt

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P2860

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

Yeast DNA polymerase epsilon participates in leading-strand DNA replication

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A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

The TOR-controlled transcription activators GLN3, RTG1, and RTG3 are regulated in response to intracellular levels of glutamine.

Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity.

Cloning and molecular characterization of three genes, including two genes encoding serine hydroxymethyltransferases, whose inactivation is required to render yeast auxotrophic for glycine.

Role of mitochondrial and cytoplasmic serine hydroxymethyltransferase isozymes in de novo purine synthesis in Saccharomyces cerevisiae.

Identification of RNR4, encoding a second essential small subunit of ribonucleotide reductase in Saccharomyces cerevisiae

Yeast Sml1, a protein inhibitor of ribonucleotide reductase.

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scholarly article

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10.1073/PNAS.1618714114

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English

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114

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Andrei Chabes

Hans Hombauer

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2017-04-17T00:00:00Z

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28416670

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5465912

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Alterations in cellular metabolism triggered by URA7 or GLN3 inactivation cause imbalanced dNTP pools and increased mutagenesis.

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P2860

P2860

Alterations in cellular metabolism triggered by URA7 or GLN3 inactivation cause imbalanced dNTP pools and increased mutagenesis.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932