about
Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7A second human Dbf4/ASK-related protein, Drf1/ASKL1, is required for efficient progression of S and M phasesStructure of the Cdt1 C-terminal domain: Conservation of the winged helix fold in replication licensing factorsCdc7 is required throughout the yeast S phase to activate replication origins.Coordinating DNA replication to produce one copy of the genome requires genes that act in ubiquitin metabolism.Human Cdc7-related kinase complex. In vitro phosphorylation of MCM by concerted actions of Cdks and Cdc7 and that of a criticial threonine residue of Cdc7 bY CdksHierarchy of S-phase-promoting factors: yeast Dbf4-Cdc7 kinase requires prior S-phase cyclin-dependent kinase activation.Cell cycle control of Cdc7p kinase activity through regulation of Dbf4p stability.The role of Dbf4-dependent protein kinase in DNA polymerase ζ-dependent mutagenesis in Saccharomyces cerevisiae.Fission yeast cdc24(+) encodes a novel replication factor required for chromosome integrity.A role for the Cdc7 kinase regulatory subunit Dbf4p in the formation of initiation-competent origins of replication.Hypomorphic mutation in an essential cell-cycle kinase causes growth retardation and impaired spermatogenesis.Segregation of unreplicated chromosomes in Saccharomyces cerevisiae reveals a novel G1/M-phase checkpointMutations in the homologous ZDS1 and ZDS2 genes affect cell cycle progressionCDC45 is required in conjunction with CDC7/DBF4 to trigger the initiation of DNA replicationCandida albicans Dbf4-dependent Cdc7 kinase plays a novel role in the inhibition of hyphal development.Regulation of initiation of S phase, replication checkpoint signaling, and maintenance of mitotic chromosome structures during S phase by Hsk1 kinase in the fission yeast.A fission yeast gene, him1(+)/dfp1(+), encoding a regulatory subunit for Hsk1 kinase, plays essential roles in S-phase initiation as well as in S-phase checkpoint control and recovery from DNA damage.Inactivation of Cdc7 kinase in mouse ES cells results in S-phase arrest and p53-dependent cell death.Molecular mechanism of activation of human Cdc7 kinase: bipartite interaction with Dbf4/activator of S phase kinase (ASK) activation subunit stimulates ATP binding and substrate recognitionBipartite binding of a kinase activator activates Cdc7-related kinase essential for S phase.Purification of Hsk1, a minichromosome maintenance protein kinase from fission yeast.Importin-beta mediates Cdc7 nuclear import by binding to the kinase insert II domain, which can be antagonized by importin-alpha.
P2860
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P2860
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Cdc7 protein kinase for DNA metabolism comes of age.
@en
type
label
Cdc7 protein kinase for DNA metabolism comes of age.
@en
prefLabel
Cdc7 protein kinase for DNA metabolism comes of age.
@en
P2860
P1476
Cdc7 protein kinase for DNA metabolism comes of age
@en
P2093
Jackson AL
Sclafani RA
P2860
P304
P356
10.1111/J.1365-2958.1994.TB00358.X
P407
P577
1994-03-01T00:00:00Z