Human Cdc7-related kinase complex. In vitro phosphorylation of MCM by concerted actions of Cdks and Cdc7 and that of a criticial threonine residue of Cdc7 bY Cdks - Test2 - elhamkhani - TriplyDB

Human Cdc7-related kinase complex. In vitro phosphorylation of MCM by concerted actions of Cdks and Cdc7 and that of a criticial threonine residue of Cdc7 bY Cdks

Human Cdc7-related kinase complex. In vitro phosphorylation of MCM by concerted actions of Cdks and Cdc7 and that of a criticial threonine residue of Cdc7 bY Cdks

http://www.wikidata.org/entity/Q28137917

about

RGC-32 increases p34CDC2 kinase activity and entry of aortic smooth muscle cells into S-phase Essential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cells Drf1, a novel regulatory subunit for human Cdc7 kinase Interactions of the human MCM-BP protein with MCM complex components and Dbf4 A second human Dbf4/ASK-related protein, Drf1/ASKL1, is required for efficient progression of S and M phases Human cytomegalovirus infection leads to accumulation of geminin and inhibition of the licensing of cellular DNA replication.How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?Transcriptional co-activator LEDGF interacts with Cdc7-activator of S-phase kinase (ASK) and stimulates its enzymatic activity Cdc7-Dbf4 and the human S checkpoint response to UVC CDC7 kinase phosphorylates serine residues adjacent to acidic amino acids in the minichromosome maintenance 2 protein DNA binding and helicase actions of mouse MCM4/6/7 helicase.The Sum1/Ndt80 transcriptional switch and commitment to meiosis in Saccharomyces cerevisiae Genomic instability in cancer.Mechanism of cancer cell death induced by depletion of an essential replication regulator Sequential primed kinases create a damage-responsive phosphodegron on Eco1.Biochemical activities associated with mouse Mcm2 protein Human Dbf4/ASK promoter is activated through the Sp1 and MluI cell-cycle box (MCB) transcription elements Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases Mutation of tumor suppressor gene Men1 acutely enhances proliferation of pancreatic islet cells Dbf4-Cdc7 phosphorylation of Mcm2 is required for cell growth.Cdc28-Clb5 (CDK-S) and Cdc7-Dbf4 (DDK) collaborate to initiate meiotic recombination in yeast CDC28 phosphorylates Cac1p and regulates the association of chromatin assembly factor I with chromatin.Survey of phosphorylation near drug binding sites in the Protein Data Bank (PDB) and their effects.Cell cycle regulation of chromatin binding and nuclear localization of human Cdc7-ASK kinase complex.Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop.Protein phosphatase 2A regulates binding of Cdc45 to the prereplication complex.p21cip1 Degradation in differentiated keratinocytes is abrogated by costabilization with cyclin E induced by human papillomavirus E7.Cdc7-Drf1 is a developmentally regulated protein kinase required for the initiation of vertebrate DNA replication The Cdc7/Dbf4 protein kinase: target of the S phase checkpoint?Rif1 is a global regulator of timing of replication origin firing in fission yeast.Phosphorylated Rad18 directs DNA polymerase η to sites of stalled replication Control of DNA replication licensing in a cell cycle.Cdc7 kinase complex: a key regulator in the initiation of DNA replication.The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism.Phosphorylation of MCM4 by Cdc7 kinase facilitates its interaction with Cdc45 on the chromatin.Reduced spermatogonial proliferation and decreased fertility in mice overexpressing cyclin E in spermatogonia The Cdc23 (Mcm10) protein is required for the phosphorylation of minichromosome maintenance complex by the Dfp1-Hsk1 kinase.Characterization of a Drosophila ortholog of the Cdc7 kinase: a role for Cdc7 in endoreplication independent of Chiffon.Cyclin-dependent kinase regulates the length of S phase through TICRR/TRESLIN phosphorylation.Eukaryotic MCM proteins: beyond replication initiation.

P2860

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P2860

Human Cdc7-related kinase complex. In vitro phosphorylation of MCM by concerted actions of Cdks and Cdc7 and that of a criticial threonine residue of Cdc7 bY Cdks

http://www.wikidata.org/entity/Q28137917

description

2000 nî lūn-bûn

@nan

2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2000年の論文

@ja

2000年論文

@yue

2000年論文

@zh-hant

2000年論文

@zh-hk

2000年論文

@zh-mo

2000年論文

@zh-tw

2000年论文

@wuu

name

Human Cdc7-related kinase comp ...... eonine residue of Cdc7 bY Cdks

@ast

Human Cdc7-related kinase comp ...... eonine residue of Cdc7 bY Cdks

@en

Human Cdc7-related kinase comp ...... eonine residue of Cdc7 bY Cdks

@nl

type

label

Human Cdc7-related kinase comp ...... eonine residue of Cdc7 bY Cdks

@ast

Human Cdc7-related kinase comp ...... eonine residue of Cdc7 bY Cdks

@en

Human Cdc7-related kinase comp ...... eonine residue of Cdc7 bY Cdks

@nl

prefLabel

Human Cdc7-related kinase comp ...... eonine residue of Cdc7 bY Cdks

@ast

Human Cdc7-related kinase comp ...... eonine residue of Cdc7 bY Cdks

@en

Human Cdc7-related kinase comp ...... eonine residue of Cdc7 bY Cdks

@nl

P1433

Q28137917-40D991F2-EF7B-4621-8432-92A586C28AF9

P1476

Q28137917-BECE9AFE-5757-4383-8F64-91B9B0FEF32B

P2093

Q28137917-41E76AB6-50F7-492E-8F50-86731729B4B4

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P2860

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Q28137917-A792B4FF-14A3-429F-A263-32BE29B5BF0F

P31

Q28137917-4DDE73FF-5D0D-4F9D-B511-280AB0B52382

P3181

Q28137917-0C57B428-725F-413C-AD83-F6896D7B1CEC

P356

Q28137917-FF43C627-1CED-4522-86B9-AF5F3285A4AD

P407

Q28137917-7DBD3382-364F-4B57-8531-38968AD26F5C

P433

Q28137917-7A90FE34-6F87-4983-B37B-13D479F6E62A

P478

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P577

Q28137917-38F552AB-40AC-4D43-AA03-8B5F1BCC9B8C

P698

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P921

Q28137917-13EAC10D-E4C1-49D7-973D-6D9469AFEE93

P3181

P356

P1433

Journal of Biological Chemistry

P1476

Human Cdc7-related kinase comp ...... eonine residue of Cdc7 bY Cdks

@en

P2093

E Matsui

http://www.w3.org/2001/XMLSchema#string

H Masai

http://www.w3.org/2001/XMLSchema#string

K Arai

http://www.w3.org/2001/XMLSchema#string

K Tamai

http://www.w3.org/2001/XMLSchema#string

Y Ishimi

http://www.w3.org/2001/XMLSchema#string

Z You

http://www.w3.org/2001/XMLSchema#string

P2860

A novel growth- and cell cycle-regulated protein, ASK, activates human Cdc7-related kinase and is essential for G1/S transition in mammalian cells

Geminin, an inhibitor of DNA replication, is degraded during mitosis

A DNA helicase activity is associated with an MCM4, -6, and -7 protein complex

Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7

Identification of HsORC4, a member of the human origin of replication recognition complex

Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication

Biochemical analysis of the intrinsic Mcm4-Mcm6-mcm7 DNA helicase activity

Identification and characterization of a human protein kinase related to budding yeast Cdc7p

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

Cell cycle regulation of the yeast Cdc7 protein kinase by association with the Dbf4 protein.

P304

29042-52

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

3455642

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P356

10.1074/JBC.M002713200

http://www.w3.org/2001/XMLSchema#string

P407

P433

37

http://www.w3.org/2001/XMLSchema#string

P478

275

http://www.w3.org/2001/XMLSchema#string

P577

2000-09-15T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

10846177

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation