Blockade of mevalonate production by lovastatin attenuates bombesin and vasopressin potentiation of nutrient-induced insulin secretion in HIT-T15 cells. Probable involvement of small GTP-binding proteins.
about
Rosuvastatin Treatment Affects Both Basal and Glucose-Induced Insulin Secretion in INS-1 832/13 CellsRegulatory roles for Tiam1, a guanine nucleotide exchange factor for Rac1, in glucose-stimulated insulin secretion in pancreatic beta-cellsDown-regulation of expression and function of nucleoside diphosphate kinase in insulin-secreting beta-cells under in vitro conditions of glucolipotoxicityYES, a Src family kinase, is a proximal glucose-specific activator of cell division cycle control protein 42 (Cdc42) in pancreatic islet β cellsProtein farnesylation-dependent Raf/extracellular signal-related kinase signaling links to cytoskeletal remodeling to facilitate glucose-induced insulin secretion in pancreatic beta-cells.Small G proteins in islet beta-cell function.Protein prenylation in glucose-induced insulin secretion from the pancreatic islet beta cell: a perspective.Regulatory roles for small G proteins in the pancreatic beta-cell: lessons from models of impaired insulin secretion.EHT 1864, a small molecule inhibitor of Ras-related C3 botulinum toxin substrate 1 (Rac1), attenuates glucose-stimulated insulin secretion in pancreatic β-cells.Emerging roles for protein histidine phosphorylation in cellular signal transduction: lessons from the islet beta-cell.Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion.Dual Effect of Rosuvastatin on Glucose Homeostasis Through Improved Insulin Sensitivity and Reduced Insulin Secretion.Glucose- and GTP-dependent stimulation of the carboxyl methylation of CDC42 in rodent and human pancreatic islets and pure beta cells. Evidence for an essential role of GTP-binding proteins in nutrient-induced insulin secretion.The diabetogenic action of statins - mechanisms and clinical implications.Novel regulation by Rac1 of glucose- and forskolin-induced insulin secretion in INS-1 beta-cells.Novel roles for the rho subfamily of GTP-binding proteins in succinate-induced insulin secretion from betaTC3 cells: further evidence in support of the succinate mechanism of insulin release.Characterization of prenylcysteine methyltransferase in insulin-secreting cellsLeukotriene D4-induced mobilization of intracellular Ca2+ in epithelial cells is critically dependent on activation of the small GTP-binding protein Rho.Intracellular alkalinization suppresses lovastatin-induced apoptosis in HL-60 cells through the inactivation of a pH-dependent endonuclease.Dynamics of Ca2+ and guanosine 5'-[gamma-thio]triphosphate action on insulin secretion from alpha-toxin-permeabilized HIT-T15 cells.Store-activated Ca2+ inflow in Xenopus laevis oocytes: inhibition by primaquine and evaluation of the role of membrane fusion.A novel regulatory mechanism for trimeric GTP-binding proteins in the membrane and secretory granule fractions of human and rodent beta cells.Comparison of the effects of simvastatin vs. rosuvastatin vs. simvastatin/ezetimibe on parameters of insulin resistance.Modulation of insulin secretion from normal rat islets by inhibitors of the post-translational modifications of GTP-binding proteinsLimitation of heart growth in neonatal piglets by simvastatin and atorvastatin: comparison with pravastatin.Defective protein histidine phosphorylation in islets from the Goto-Kakizaki diabetic rat.Role of G-proteins in islet function in health and diabetes.GGPPS-mediated Rab27A geranylgeranylation regulates β cell dysfunction during type 2 diabetes development by affecting insulin granule docked pool formation.
P2860
Q28550796-33724372-B867-4A8D-8FA4-A60207E871C3Q28578486-28B59F40-C92A-4E65-B5B6-991013766BB7Q28580219-9F02BF54-1012-4271-97F7-2B96392619A4Q33676391-48CB5430-D5D0-497C-89E2-1B119762C2E7Q33750751-9E4D49C4-7A4A-4B8D-A9AB-76F2799BEA3EQ33779672-B7F6E3CE-870F-4434-93C9-43F5D015A68CQ34720513-175DCFA5-6170-4B49-895C-72AFB80887A6Q35213687-1CC823E7-B064-4EBE-8608-F0BC64515C30Q35236262-2C8EDD22-511F-400E-B1E1-6F8CE4BE6CDDQ35862451-40A7F8C6-E9F0-4FED-9AAA-C3B817DC6D82Q35976901-925C0BD4-B35F-4C72-BC20-1E69BCC86AE7Q36084295-0D4DC9E0-7150-4B41-B749-4BD42B84A1F3Q37357925-96429FC7-10CD-4FC5-B890-0B17C8285B02Q38669513-758081B1-4AB2-4587-9A9F-035317F2888DQ40596974-19A79261-CD3E-43E3-9A6C-269154D8A51EQ40627708-1738814E-FB97-4C39-8E97-31AFFEB09BB8Q41198553-2450E09F-61EE-4B2C-944F-B196E04729E7Q41198596-4430D5A6-75BE-4507-8FBB-7B2218C30B55Q41359115-73330211-F547-43FF-BD2C-C30F87E59770Q41454397-DB3664B6-5C0A-42B0-852E-3568D3E68720Q42149362-F6A0CC74-AC26-493B-95E2-6AF72B8BDAB3Q42160330-003F77A6-6048-4303-9213-1179410C34A2Q42495891-D08E7136-8B89-4E6F-9D3D-0B31A6B4AE4DQ42814670-5C85E045-E63B-4370-A2F2-3DD88AF6D03DQ43610532-8DE570EE-89D9-4A29-BCD9-39ABD6A9E077Q44473628-2342BB77-1563-4EB2-BFC5-0EF78FFF327BQ47843056-7BDC5AE5-DBAC-41E5-AC3D-6731B39BE5C4Q53327603-DF8F7FC9-D619-4033-855B-193BFE94A9E0
P2860
Blockade of mevalonate production by lovastatin attenuates bombesin and vasopressin potentiation of nutrient-induced insulin secretion in HIT-T15 cells. Probable involvement of small GTP-binding proteins.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Blockade of mevalonate product ...... of small GTP-binding proteins.
@en
type
label
Blockade of mevalonate product ...... of small GTP-binding proteins.
@en
prefLabel
Blockade of mevalonate product ...... of small GTP-binding proteins.
@en
P2093
P2860
P356
P1433
P1476
Blockade of mevalonate product ...... of small GTP-binding proteins
@en
P2093
P2860
P304
P356
10.1042/BJ2890379
P407
P478
289 ( Pt 2)
P577
1993-01-01T00:00:00Z