A cullin 4B-RING E3 ligase complex fine-tunes pancreatic δ cell paracrine interactions.

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Ablation of somatostatin cells leads to impaired pancreatic islet function and neonatal death in rodents.TALK-1 reduces delta-cell endoplasmic reticulum and cytoplasmic calcium levels limiting somatostatin secretion.

P2860

Q55104419-D4D103FB-25C4-4CAF-9A04-4C98F464FD5F Q55363264-D9453654-4BBE-4270-9F0D-9E94CDBAC898

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A cullin 4B-RING E3 ligase complex fine-tunes pancreatic δ cell paracrine interactions.

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http://www.wikidata.org/entity/Q41661662

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

@zh-tw

2017年论文

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2017年论文

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2017年论文

@zh-cn

name

A cullin 4B-RING E3 ligase complex fine-tunes pancreatic δ cell paracrine interactions.

@en

type

Item

label

A cullin 4B-RING E3 ligase complex fine-tunes pancreatic δ cell paracrine interactions.

@en

prefLabel

A cullin 4B-RING E3 ligase complex fine-tunes pancreatic δ cell paracrine interactions.

@en

P1476

A cullin 4B-RING E3 ligase complex fine-tunes pancreatic δ cell paracrine interactions

@en

P2093

Amy Lin

http://www.w3.org/2001/XMLSchema#string

Baichun Jiang

http://www.w3.org/2001/XMLSchema#string

Daolai Zhang

http://www.w3.org/2001/XMLSchema#string

Dongfang He

http://www.w3.org/2001/XMLSchema#string

Fan Yang

http://www.w3.org/2001/XMLSchema#string

Fan Yi

http://www.w3.org/2001/XMLSchema#string

Feng Liu

http://www.w3.org/2001/XMLSchema#string

Haibo Qi

http://www.w3.org/2001/XMLSchema#string

Hechen Song

http://www.w3.org/2001/XMLSchema#string

Huili Hu

http://www.w3.org/2001/XMLSchema#string

P2860

CRL4B catalyzes H2AK119 monoubiquitination and coordinates with PRC2 to promote tumorigenesis

The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells

Paracrine and autocrine interactions in the human islet: more than meets the eye

A Cul4 E3 ubiquitin ligase regulates histone hand-off during nucleosome assembly.

Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis

Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremor

Mutation in CUL4B, which encodes a member of cullin-RING ubiquitin ligase complex, causes X-linked mental retardation

Subtype-selective expression of the five somatostatin receptors (hSSTR1-5) in human pancreatic islet cells: a quantitative double-label immunohistochemical analysis

Pcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in mice

X-linked mental retardation gene CUL4B targets ubiquitylation of H3K4 methyltransferase component WDR5 and regulates neuronal gene expression

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2631-2646

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scholarly article

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10.1172/JCI91348

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English

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127

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Jiajun Zhao

P577

2017-06-12T00:00:00Z

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28604389

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P932

5490770

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A cullin 4B-RING E3 ligase complex fine-tunes pancreatic δ cell paracrine interactions.

about

P2860

P2860

A cullin 4B-RING E3 ligase complex fine-tunes pancreatic δ cell paracrine interactions.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932