The CaaX motif of lamin A functions in conjunction with the nuclear localization signal to target assembly to the nuclear envelope.
about
Nuclear lamins A and B1: different pathways of assembly during nuclear envelope formation in living cellsPathway of incorporation of microinjected lamin A into the nuclear envelopeREST/NRSF-interacting LIM domain protein, a putative nuclear translocation receptorCharacterization of the REST/NRSF-interacting LIM domain protein (RILP): localization and interaction with REST/NRSFTargeting of Nbp1 to the inner nuclear membrane is essential for spindle pole body duplication.Mechanism and a peptide motif for targeting peripheral proteins to the yeast inner nuclear membrane.Regulation of lamin properties and functions: does phosphorylation do it all?Laminopathies and the long strange trip from basic cell biology to therapyDifferent domains cooperate to target the human ribosomal L7a protein to the nucleus and to the nucleoliAssembly properties of dominant and recessive mutations in the small mouse neurofilament (NF-L) subunitLINC'ing form and function at the nuclear envelope.Farnesylation of lamin B1 is important for retention of nuclear chromatin during neuronal migration.Meiotic lamin C2: the unique amino-terminal hexapeptide GNAEGR is essential for nuclear envelope association.Nuclear localization signal deletion mutants of lamin A and progerin reveal insights into lamin A processing and emerin targetingG protein gamma subunits contain a 20-carbon isoprenoid.The posttranslational processing of prelamin A and disease.Mechanobiology and the microcirculation: cellular, nuclear and fluid mechanics.Association of prenylated proteins with the plasma membrane and the inner nuclear membrane is mediated by the same membrane-targeting motifsStructure of an invertebrate gene encoding cytoplasmic intermediate filament (IF) proteins: implications for the origin and the diversification of IF proteins.Direct synthesis of lamin A, bypassing prelamin a processing, causes misshapen nuclei in fibroblasts but no detectable pathology in mice.Functional dissection of YA, an essential, developmentally regulated nuclear lamina protein in Drosophila melanogaster.Morphological analysis of 13 LMNA variants identified in a cohort of 324 unrelated patients with idiopathic or familial dilated cardiomyopathy.cDNA cloning of a germ cell specific lamin B3 from mouse spermatocytes and analysis of its function by ectopic expression in somatic cells.Inhibiting farnesylation reverses the nuclear morphology defect in a HeLa cell model for Hutchinson-Gilford progeria syndrome.Requirements for efficient proteolytic cleavage of prelamin A by ZMPSTE24.Gene structure of nuclear lamin LIII of Xenopus laevis; a model for the evolution of IF proteins from a lamin-like ancestor.An absence of nuclear lamins in keratinocytes leads to ichthyosis, defective epidermal barrier function, and intrusion of nuclear membranes and endoplasmic reticulum into the nuclear chromatinHead and/or CaaX domain deletions of lamin proteins disrupt preformed lamin A and C but not lamin B structure in mammalian cells.New ZMPSTE24 (FACE1) mutations in patients affected with restrictive dermopathy or related progeroid syndromes and mutation update.Protein synthesis, posttranslational modifications, and aging.The functions of Klarsicht and nuclear lamin in developmentally regulated nuclear migrations of photoreceptor cells in the Drosophila eye.Local translation of extranuclear lamin B promotes axon maintenanceDisassembly of in vitro formed lamin head-to-tail polymers by CDC2 kinase.A-type lamins: guardians of the soma?Mouse models of the laminopathies.Biogenesis of the Saccharomyces cerevisiae pheromone a-factor, from yeast mating to human disease.Internuclear exchange of an inner nuclear membrane protein (p55) in heterokaryons: in vivo evidence for the interaction of p55 with the nuclear laminaPhosphorylation on protein kinase C sites inhibits nuclear import of lamin B2.Analysis of nuclear lamin isoprenylation in Xenopus oocytes: isoprenylation of lamin B3 precedes its uptake into the nucleus.Disruption of nuclear lamin organization alters the distribution of replication factors and inhibits DNA synthesis.
P2860
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P2860
The CaaX motif of lamin A functions in conjunction with the nuclear localization signal to target assembly to the nuclear envelope.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
The CaaX motif of lamin A func ...... embly to the nuclear envelope.
@en
type
label
The CaaX motif of lamin A func ...... embly to the nuclear envelope.
@en
prefLabel
The CaaX motif of lamin A func ...... embly to the nuclear envelope.
@en
P2093
P1433
P1476
The CaaX motif of lamin A func ...... embly to the nuclear envelope.
@en
P2093
P304
P356
10.1016/0092-8674(89)90753-8
P407
P577
1989-12-01T00:00:00Z