Mutations in recombinational repair and in checkpoint control genes suppress the lethal combination of srs2Delta with other DNA repair genes in Saccharomyces cerevisiae.
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Cdk1 targets Srs2 to complete synthesis-dependent strand annealing and to promote recombinational repairRTEL1 maintains genomic stability by suppressing homologous recombinationSws1 is a conserved regulator of homologous recombination in eukaryotic cellsPhosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G(1)/S checkpoint activation in response to DNA damageCombined analysis of expression data and transcription factor binding sites in the yeast genomeSrs2 and RecQ homologs cooperate in mei-3-mediated homologous recombination repair of Neurospora crassa.Localization of recombination proteins and Srs2 reveals anti-recombinase function in vivo.Remodeling of the Rad51 DNA strand-exchange protein by the Srs2 helicase.Role of SGS1 and SLX4 in maintaining rDNA structure in Saccharomyces cerevisiae.RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complexSrs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates.Rad52 sumoylation prevents the toxicity of unproductive Rad51 filaments independently of the anti-recombinase Srs2The PCNA interaction protein box sequence in Rad54 is an integral part of its ATPase domain and is required for efficient DNA repair and recombinationSaccharomyces cerevisiae Rrm3p DNA helicase promotes genome integrity by preventing replication fork stalling: viability of rrm3 cells requires the intra-S-phase checkpoint and fork restart activitiesRole of RAD52 epistasis group genes in homologous recombination and double-strand break repairInvolvement of Schizosaccharomyces pombe Srs2 in cellular responses to DNA damageA new Saccharomyces cerevisiae strain with a mutant Smt3-deconjugating Ulp1 protein is affected in DNA replication and requires Srs2 and homologous recombination for its viability.The role of replication bypass pathways in dicentric chromosome formation in budding yeastUnwinding of synthetic replication and recombination substrates by Srs2.Alternate pathways involving Sgs1/Top3, Mus81/ Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication.A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damageMus81 and Yen1 promote reciprocal exchange during mitotic recombination to maintain genome integrity in budding yeast.UV irradiation causes the loss of viable mitotic recombinants in Schizosaccharomyces pombe cells lacking the G(2)/M DNA damage checkpoint.The mechanism of Mus81-Mms4 cleavage site selection distinguishes it from the homologous endonuclease Rad1-Rad10.Analyses of the yeast Rad51 recombinase A265V mutant reveal different in vivo roles of Swi2-like factors.Suppression of spontaneous genome rearrangements in yeast DNA helicase mutantsThe human F-Box DNA helicase FBH1 faces Saccharomyces cerevisiae Srs2 and postreplication repair pathway roles.Mrc1 is required for sister chromatid cohesion to aid in recombination repair of spontaneous damage.Pro-recombination Role of Srs2 Protein Requires SUMO (Small Ubiquitin-like Modifier) but Is Independent of PCNA (Proliferating Cell Nuclear Antigen) Interaction.S-phase checkpoint genes safeguard high-fidelity sister chromatid cohesionRrm3 protects the Saccharomyces cerevisiae genome from instability at nascent sites of retrotranspositionRequirement of Rrm3 helicase for repair of spontaneous DNA lesions in cells lacking Srs2 or Sgs1 helicaseSystematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletionsMultifunctional roles of Saccharomyces cerevisiae Srs2 protein in replication, recombination and repair.The srs2 suppressor of UV sensitivity acts specifically on the RAD5- and MMS2-dependent branch of the RAD6 pathway.Suppression of genetic defects within the RAD6 pathway by srs2 is specific for error-free post-replication repair but not for damage-induced mutagenesis.SGS1 is a multicopy suppressor of srs2: functional overlap between DNA helicasesThe severe slow growth of Deltasrs2 Deltarqh1 in Schizosaccharomyces pombe is suppressed by loss of recombination and checkpoint genes.Molecular dissection of mitotic recombination in the yeast Saccharomyces cerevisiaeThe involvement of Srs2 in post-replication repair and homologous recombination in fission yeast.
P2860
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P2860
Mutations in recombinational repair and in checkpoint control genes suppress the lethal combination of srs2Delta with other DNA repair genes in Saccharomyces cerevisiae.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Mutations in recombinational r ...... s in Saccharomyces cerevisiae.
@en
type
label
Mutations in recombinational r ...... s in Saccharomyces cerevisiae.
@en
prefLabel
Mutations in recombinational r ...... s in Saccharomyces cerevisiae.
@en
P2860
P1433
P1476
Mutations in recombinational r ...... es in Saccharomyces cerevisiae
@en
P2860
P304
P407
P577
2001-02-01T00:00:00Z