Crystal structures of Mycobacteria tuberculosis and Klebsiella pneumoniae UDP-galactopyranose mutase in the oxidised state and Klebsiella pneumoniae UDP-galactopyranose mutase in the (active) reduced state.
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The structural biology of enzymes involved in natural product glycosylationTargeting UDP-galactopyranose mutases from eukaryotic human pathogensStructures of the first representatives of Pfam family PF06938 (DUF1285) reveal a new fold with repeated structural motifs and possible involvement in signal transductionLigand Binding and Substrate Discrimination by UDP-Galactopyranose MutaseX-ray crystallography reveals a reduced substrate complex of UDP-galactopyranose mutase poised for covalent catalysis by flavinVirtual Screening for UDP-Galactopyranose Mutase Ligands Identifies a New Class of Antimycobacterial AgentsIdentification of the NAD(P)H Binding Site of Eukaryotic UDP-Galactopyranose MutaseCrystal Structures and Small-angle X-ray Scattering Analysis of UDP-galactopyranose Mutase from the Pathogenic Fungus Aspergillus fumigatusStructural Insight into the Unique Substrate Binding Mechanism and Flavin Redox State of UDP-galactopyranose Mutase from Aspergillus fumigatusCrystal Structures of Trypanosoma cruzi UDP-Galactopyranose Mutase Implicate Flexibility of the Histidine Loop in Enzyme ActivationSpecificity of a UDP-GalNAc pyranose-furanose mutase: a potential therapeutic target for Campylobacter jejuni infectionsCharacterization of a bifunctional pyranose-furanose mutase from Campylobacter jejuni 11168.Purification, crystallization and preliminary X-ray diffraction data of UDP-galactopyranose mutase from Aspergillus fumigatusThe diverse roles of flavin coenzymes--nature's most versatile thespians.Analysis and validation of carbohydrate three-dimensional structures.QM/MM molecular dynamics study of the galactopyranose → galactofuranose reaction catalysed by Trypanosoma cruzi UDP-galactopyranose mutase.Towards the crystal structure elucidation of eukaryotic UDP-galactopyranose mutaseWhole Genome Sequencing of 39 Invasive Streptococcus pneumoniae Sequence Type 199 Isolates Revealed Switches from Serotype 19A to 15BNoncanonical reactions of flavoenzymes.Targeting the formation of the cell wall core of M. tuberculosis.UDP-galactopyranose mutase in nematodes.Investigation of binding of UDP-Galf and UDP-[3-F]Galf to UDP-galactopyranose mutase by STD-NMR spectroscopy, molecular dynamics, and CORCEMA-ST calculations.Aspergillus nidulans cell wall composition and function change in response to hosting several Aspergillus fumigatus UDP-galactopyranose mutase activity mutantsStructure, mechanism, and dynamics of UDP-galactopyranose mutase.Galactofuranose in eukaryotes: aspects of biosynthesis and functional impact.UDP-galactopyranose mutase, a potential drug target against human pathogenic nematode Brugia malayi.Multiple functionalities of reduced flavin in the non-redox reaction catalyzed by UDP-galactopyranose mutase.Synthetic UDP-furanoses as potent inhibitors of mycobacterial galactan biogenesis.Natural and Synthetic Flavonoids as Potent Mycobacterium tuberculosis UGM Inhibitors.Expression, purification and preliminary X-ray crystallographic analysis of UDP-galactopyranose mutase from Deinococcus radiodurans.Synthesis and analysis of substrate analogues for UDP-galactopyranose mutase: implication for an oxocarbenium ion intermediate in the catalytic mechanism.A simple and efficient expression and purification system using two newly constructed vectorsBiosynthesis of galactofuranose in kinetoplastids: novel therapeutic targets for treating leishmaniasis and chagas' disease.Conformational Control of UDP-Galactopyranose Mutase Inhibition.The Cell Wall Arabinose-Deficient Arabidopsis thaliana Mutant murus5 Encodes a Defective Allele of REVERSIBLY GLYCOSYLATED POLYPEPTIDE2.A Second, Druggable Binding Site in UDP-Galactopyranose Mutase from Mycobacterium tuberculosis?Identification of Novel Inhibitors of UDP-Galactopyranose Mutase by Structure-Based Virtual Screening.
P2860
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P2860
Crystal structures of Mycobacteria tuberculosis and Klebsiella pneumoniae UDP-galactopyranose mutase in the oxidised state and Klebsiella pneumoniae UDP-galactopyranose mutase in the (active) reduced state.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Crystal structures of Mycobact ...... in the (active) reduced state.
@en
type
label
Crystal structures of Mycobact ...... in the (active) reduced state.
@en
prefLabel
Crystal structures of Mycobact ...... in the (active) reduced state.
@en
P2093
P2860
P921
P1476
Crystal structures of Mycobact ...... in the (active) reduced state.
@en
P2093
Chris Whitfield
David A R Sanders
Huanting Liu
Mike R McNeil
Stephen W B Fullerton
Velupillai Srikannathasan
Vicki A Bamford
P2860
P304
P356
10.1016/J.JMB.2005.02.057
P407
P577
2005-05-01T00:00:00Z