Mammalian iRhoms have distinct physiological functions including an essential role in TACE regulation.
about
A Disintegrin and Metalloprotease (ADAM): Historical Overview of Their FunctionsEGF receptor ligands: recent advancesRhomboids, signalling and cell biologyPlasmodium falciparum SERA5 plays a non-enzymatic role in the malarial asexual blood-stage lifecycleTranscriptional analysis of apoptotic cerebellar granule neurons following rescue by gastric inhibitory polypeptideEctodomain Shedding by ADAM17: Its Role in Neutrophil Recruitment and the Impairment of This Process during SepsisRhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin.Phosphorylation of iRhom2 at the plasma membrane controls mammalian TACE-dependent inflammatory and growth factor signalling.iRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier functionBio-Zombie: the rise of pseudoenzymes in biology.A mechanism of male germ cell apoptosis induced by bisphenol-A and nonylphenol involving ADAM17 and p38 MAPK activation.iRhom2 mutation leads to aberrant hair follicle differentiation in mice.iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signalingiRhoms; Its Functions and Essential Roles.Rhomboid intramembrane protease RHBDL4 triggers ER-export and non-canonical secretion of membrane-anchored TGFαADAM Proteases and Gastrointestinal Function.Rhomboid family member 2 regulates cytoskeletal stress-associated Keratin 16.Alternative Processing of the Amyloid Precursor Protein Family by Rhomboid Protease RHBDL4.Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17.Regulation of A disintegrin and metalloproteinase (ADAM) family sheddases ADAM10 and ADAM17: The emerging role of tetraspanins and rhomboids.The sorting protein PACS-2 promotes ErbB signalling by regulating recycling of the metalloproteinase ADAM17.Fine Tuning Cell Migration by a Disintegrin and Metalloproteinases.Emerging roles of rhomboid-like pseudoproteases in inflammatory and innate immune responses.Control of ADAM17 activity by regulation of its cellular localisationGenetic interaction implicates iRhom2 in the regulation of EGF receptor signalling in mice.Divergent evolution of the M3A family of metallopeptidases in plants.Phosphorylation of iRhom2 Controls Stimulated Proteolytic Shedding by the Metalloprotease ADAM17/TACE.Collagen-Induced Arthritis Analysis in Rhbdf2 Knockout Mouse.Redundancy of protein disulfide isomerases in the catalysis of the inactivating disulfide switch in A Disintegrin and Metalloprotease 17.Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis.Total flavones of Abelmoschus manihot improve diabetic nephropathy by inhibiting the iRhom2/TACE signalling pathway activity in rats.iRhom2 regulates CSF1R cell surface expression and non-steady state myelopoiesis in mice.Macrophage Heterogeneity in the Immunopathogenesis of Tuberculosis.Liquid biopsy: a new source of candidate biomarkers in amyotrophic lateral sclerosis.iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex
P2860
Q26749364-700ED308-E11E-4F3F-85B3-467F45D2DE94Q28066531-BDF2731C-E235-46EE-85A5-7F34EE95890EQ28070034-811A7318-8B0A-4008-B59C-BDFA48B2DDEEQ30046956-789A6462-5DBA-4C53-94AC-BCFA1441AE4EQ33580451-D161FBB4-4439-4588-80FD-8A95005C96ADQ33599723-33996614-C7A6-4C0F-9F34-1C41A3066815Q33694413-5B328867-CC75-4A8D-BBC4-B09A304128A1Q33704501-2C0CCFAB-636B-488E-A49A-CEEB564080A3Q33947954-A5CBEAD0-CB82-4B2D-B3D9-70B49BFA0D5EQ34555212-EB8FF700-4BE2-4F04-8735-04AEC019F068Q34634022-039694CC-F24C-4C75-A9B0-A8891B699555Q35535214-E297D679-DF0F-4D90-B223-4978403AF8A3Q35616369-E1AC0343-AFE8-410F-A45A-DBB98135A1FBQ36640392-1FC6C72D-FBC4-4528-948B-411D4777ECA9Q36970233-9180BF48-C6E0-4DA2-A287-B406272DE16CQ37052477-BEFF8761-D923-47E2-8A68-B49E0DD6DF5AQ37622403-655CE4AE-D4BF-46AE-803E-824BEC1774BAQ38749991-6CE7267C-D247-4EEB-812F-CB89D95B2822Q38822173-7AEC4F72-0B4C-4805-BAF4-F3FCAEEA6DF2Q38852399-655952FD-622E-46DE-8307-7F32D673D847Q38860417-F0994001-666C-4602-A15E-E403CC766589Q39162354-4668537C-E931-48A3-874A-6E6593093A7EQ40080379-93D4352E-4605-4E65-B42B-67AABFF1F0D5Q41430763-056D1626-18A3-4817-9546-7AB950648EAFQ42615354-7AD0D3F5-7DE4-4C49-B31C-B1ACBEA90853Q46560310-A7995F0E-64D4-4359-AF15-CD9D1C301A9AQ47135385-721780D7-113E-4E8D-8107-4AA75F080EB3Q47312702-A32BA4D1-6B67-4A65-91E2-F2FC0D79E545Q48215448-94E4E44E-A983-46E0-B03D-95E39F82FB7AQ48332917-6E8AC6D1-C852-4C2C-8A0D-6281766C748AQ49995821-D3F4D2DD-0368-43F8-B7EA-5C2E8FCFDC15Q51530886-748DA9A4-51BE-4976-9C78-2C3744D1A676Q55077165-CF81191A-83D0-4CF2-B7E3-8EA0FD59E870Q55307642-0F1BA14B-65DC-43C9-A301-18F87A5F1697Q55711821-E00EC268-F2D0-4069-BF48-014860FBBC12Q56889930-BA03805E-6A7B-452B-BAC1-36281FDE84CB
P2860
Mammalian iRhoms have distinct physiological functions including an essential role in TACE regulation.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Mammalian iRhoms have distinct ...... ntial role in TACE regulation.
@en
type
label
Mammalian iRhoms have distinct ...... ntial role in TACE regulation.
@en
prefLabel
Mammalian iRhoms have distinct ...... ntial role in TACE regulation.
@en
P2093
P2860
P356
P1433
P1476
Mammalian iRhoms have distinct ...... ential role in TACE regulation
@en
P2093
Ashraf Ibrahim
Paul Bambrough
Yonka Christova
P2860
P304
P356
10.1038/EMBOR.2013.128
P577
2013-08-23T00:00:00Z