sameAs
P101
P129
P1889
P688
Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondriaRegulation of acidification and apoptosis by SHP-1 and Bcl-2Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell deathThe HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition poreIron induces Bcl-2 expression in human dermal microvascular endothelial cellsThe immunolocalization of Bcl-2 in human term placentaASPP proteins specifically stimulate the apoptotic function of p53Bcl-2 confers growth and survival advantage to interleukin 7-dependent early pre-B cells which become factor independent by a multistep process in cultureATM, CTLA4, MNDA, and HEM1 in high versus low CD38 expressing B-cell chronic lymphocytic leukemiaApoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or BakT-2 toxin induces apoptosis, and selenium partly blocks, T-2 toxin induced apoptosis in chondrocytes through modulation of the Bax/Bcl-2 ratioIdentification of a novel proapoptotic function of resveratrol in fat cells: SIRT1-independent sensitization to TRAIL-induced apoptosisProapoptotic BAX and BAK control multiple initiator caspasesMedium from irradiated cells induces dose-dependent mitochondrial changes and BCL2 responses in unirradiated human keratinocytesIsolation of a strain of Streptococcus pneumoniae multiresistant to antibioticsBcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viabilityRole of BCL-2 in the survival and function of developing and mature sympathetic neuronsBcl-2 maintains B cell memoryThe conserved N-terminal BH4 domain of Bcl-2 homologues is essential for inhibition of apoptosis and interaction with CED-4The apoptosis and proliferation of SAC-activated B cells by IL-10 are associated with changes in Bcl-2, Bcl-xL, and Mcl-1 expressionBcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell deathEvidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxesA common binding site mediates heterodimerization and homodimerization of Bcl-2 family membersBax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeastA mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressorsbcl-2 gene prevents apoptosis of basic fibroblast growth factor-deprived murine aortic endothelial cellsOverexpressed full-length human BCL2 extends the survival of baculovirus-infected Sf9 insect cellsInhibition of Bax channel-forming activity by Bcl-2A functional role for nicotine in Bcl2 phosphorylation and suppression of apoptosisInvestigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranesThe intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blockedA short Nur77-derived peptide converts Bcl-2 from a protector to a killerbcl-2 gene enables rescue from in vitro myelosuppression (bone marrow cell death) induced by chemotherapyEvolutionary conservation of function among mammalian, avian, and viral homologs of the Bcl-2 oncoproteinInhibition of mitochondrial neural cell death pathways by protein transduction of Bcl-2 family proteinsBCL-2 is a downstream target of ATF5 that mediates the prosurvival function of ATF5 in a cell type-dependent mannerExpression of Bcl-2, Bcl-x, and Bax after T cell activation and IL-2 withdrawalPP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulumEffects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma
P921
description
Protein
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Bcl-2
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
BCL2 apoptosis regulator
@en
BCL2
@cy
BCL2
@uk
Bcl-2
@de
Bcl-2
@es
Bcl-2
@fr
Bcl-2
@it
Bcl-2
@ja
Bcl-2
@nl
Bcl-2
@pl
type
label
BCL2 apoptosis regulator
@en
BCL2
@cy
BCL2
@uk
Bcl-2
@de
Bcl-2
@es
Bcl-2
@fr
Bcl-2
@it
Bcl-2
@ja
Bcl-2
@nl
Bcl-2
@pl
altLabel
1G5M
@sr
1G5O
@sr
1GJH
@sr
B-cell CLL/lymphoma 2
@en
B-ćelijski limfom 2
@sr
BCL2
@en
BCL2
@pt
BCL2
@sr
Bcl 2
@es
Bcl-2
@en
prefLabel
BCL2 apoptosis regulator
@en
BCL2
@cy
BCL2
@uk
Bcl-2
@de
Bcl-2
@es
Bcl-2
@fr
Bcl-2
@it
Bcl-2
@ja
Bcl-2
@nl
Bcl-2
@pl
P527
P637
P638
P680
P681
P682
P705
P352
P6366
P646
P129
P1417
topic/BCL-2-gene
topic/BCL-2-protein
P1889
P2888
P31
P352
P527
P6366
2909467883
2910218159
P637
XP_011524437
XP_016881406
P638
P646
/m/021m67f
P680
P681
P682
P702
P703
P705
ENSP00000329623
ENSP00000381185
ENSP00000466417