Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11. - Test2 - elhamkhani - TriplyDB

Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11.

Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11.

http://www.wikidata.org/entity/Q42791381

about

Discovery of an Inhibitor of the Proteasome Subunit Rpn11.Protein Degradation Systems as Antimalarial Therapeutic Targets.The Proteasome in Modern Drug Discovery: Second Life of a Highly Valuable Drug Target A Bioinorganic Approach to Fragment-Based Drug Discovery Targeting Metalloenzymes.Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases.Metal-based proteasomal deubiquitinase inhibitors as potential anticancer agents.Proteasome-associated deubiquitinases and cancer.Meddling with Fate: The Proteasomal Deubiquitinating Enzymes.Blocking protein quality control to counter hereditary cancers.When nature's robots go rogue: exploring protein homeostasis dysfunction and the implications for understanding human aging disease pathologies.Increased proteasomal activity supports photoreceptor survival in inherited retinal degeneration.Cand1-Mediated Adaptive Exchange Mechanism Enables Variation in F-Box Protein Expression.Discovering proteasomal deubiquitinating enzyme inhibitors for cancer therapy: lessons from rational design, nature and old drug reposition Computational Studies on the Inhibitor Selectivity of Human JAMM Deubiquitinylases Rpn11 and CSN5

P2860

Q36278259-DD1030DB-41E0-420B-AB64-0432EAE616C9 Q39422863-108238F6-6994-45DC-90AA-2D7F73056ADB Q41519882-7A9FB8B5-CF57-4643-B2C0-31F471B8CB40 Q45938767-4D1485AC-15F5-46AB-BA25-CC28D18DC0F1 Q46325214-1BCA109E-C200-484C-98D1-992634691100 Q47098444-56B236EC-465D-4588-A309-B3D1EE71ECF5 Q47161331-062BB755-DEA8-4E78-A85E-6966FAAED288 Q47292178-B604CB9D-3179-42FD-9392-575710D6F06A Q47988257-D54FA184-A126-420B-90B1-00185771CE29 Q51763128-5C8BA47C-7EF7-477E-9090-9DA7EF5A4FDE Q52715428-F970B504-A6F9-42AE-B845-ECAE8F3C0FB4 Q52729296-16C0F3DF-85EB-4D5F-819F-FAD3C268DAC8 Q57163862-E1B3BE94-84B8-4136-9140-A9CC8132F901 Q57816614-423C01BC-55F6-4DA5-88E1-FCD126186571

P2860

Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11.

http://www.wikidata.org/entity/Q42791381

description

2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年論文

@yue

2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

@zh-mo

2017年論文

@zh-tw

2017年论文

@wuu

2017年论文

@zh

2017年论文

@zh-cn

name

Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11.

@en

Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11.

@nl

type

label

Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11.

@en

Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11.

@nl

prefLabel

Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11.

@en

Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11.

@nl

P1433

Q42791381-3EF43090-9D7C-42C3-96E8-C031EE96F432

P1476

Q42791381-75819EA2-FF20-42B9-BDCA-577CD5C086AD

P2093

Q42791381-1A3E70E2-7EE7-46C8-A84D-22C94A8E3626

Q42791381-31016295-E669-4BA2-AFB5-E75AE6824919

Q42791381-3B39583E-8171-4FB6-81CD-09A0F84115B3

Q42791381-3F9B11A0-9755-48AE-BE5E-EE42E5D9C420

Q42791381-411D08A8-C388-4187-8C41-C5F317E94DE5

Q42791381-4208D82E-8AEC-4328-BE50-490BB5054D22

Q42791381-4B191421-F3D9-43E3-846A-04A8609063FD

Q42791381-6E95D4D3-2DA7-41E1-B14A-8A2290509DA6

Q42791381-79750866-13A0-40CE-BC0A-517F219629B7

Q42791381-8D95FEF7-AC7B-4099-9F70-2B15EEDABAED

P2860

Q42791381-064C6561-9D8D-4EC2-8D45-FDA99958013B

Q42791381-087480D3-FAE2-4553-9330-695196C0DB05

Q42791381-0D05DA3B-0E5E-41B5-8137-0A949269D674

Q42791381-0EF013BC-DDC3-4D15-8B34-E939B6F73AF5

Q42791381-224B22D3-69E8-4A91-B2C6-44D354ED9FF3

Q42791381-25B2A204-7343-404B-8EB4-407F5670850A

Q42791381-3069C992-2F29-4FFF-9378-32B44980F40A

Q42791381-328A04AB-FCC2-48CB-AB1E-BC3999780B71

Q42791381-34D50613-C344-4AA4-AEEB-0B27788D2FD8

Q42791381-34D90605-ED2B-44FA-8498-943AC631CD3F

P2888

Q42791381-0D0D5914-337B-4149-AF61-90DD9216653A

P304

Q42791381-0A9EF0CE-85FC-4022-A264-23C7AC085421

P31

Q42791381-20D5A71B-FC8F-40EB-A7A7-229129465D70

P356

Q42791381-9047A950-1469-46A1-957B-0CEECC84002E

P433

Q42791381-9A31302D-CA1A-4D33-BF2E-100F7AB143DD

P478

Q42791381-E15C6ED1-F2A0-4CAA-824C-EFFA455209DB

P50

Q42791381-3DCFF525-BE1A-4746-B448-7737533C3C46

Q42791381-A03528BC-7456-4B46-921D-D5D91BA87C94

Q42791381-B2FEA2CF-4396-4B95-9E0B-49BF556E4603

Q42791381-D13A4689-AF61-4A36-BF9D-B789693875B5

Q42791381-F62ACF61-39D7-42DB-BCC6-ADF7419B7CF5

P577

Q42791381-58DF3FB7-8BE7-4386-90F1-B39626241147

P698

Q42791381-4FCAB922-C671-4CE0-BBDE-7C79DE9C77F9

P932

Q42791381-48997F3A-AD17-474C-820E-7E2A5C0A122D

P356

P1433

Nature Chemical Biology

P1476

Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11

@en

P2093

Amy E Palmer

http://www.w3.org/2001/XMLSchema#string

Andrew L Mackinnon

http://www.w3.org/2001/XMLSchema#string

Brock Brown

http://www.w3.org/2001/XMLSchema#string

Christian Perez

http://www.w3.org/2001/XMLSchema#string

Eduard Sergienko

http://www.w3.org/2001/XMLSchema#string

Eigo Suyama

http://www.w3.org/2001/XMLSchema#string

Francesco Parlati

http://www.w3.org/2001/XMLSchema#string

Gavin Magnuson

http://www.w3.org/2001/XMLSchema#string

Ian Pass

http://www.w3.org/2001/XMLSchema#string

Jing Li

http://www.w3.org/2001/XMLSchema#string

P2860

JAMM: a metalloprotease-like zinc site in the proteasome and signalosome

RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites

Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation

Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice.

A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation

AMSH is an endosome-associated ubiquitin isopeptidase

Structure of the Jab1/MPN domain and its implications for proteasome function

Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains

Metalloprotein–Inhibitor Binding: Human Carbonic Anhydrase II as a Model for Probing Metal–Ligand Interactions in a Metalloprotein Active Site

Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11

P2888

P304

486-493

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NCHEMBIO.2326

http://www.w3.org/2001/XMLSchema#string

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

13

http://www.w3.org/2001/XMLSchema#string

P50

Raymond J. Deshaies

Anthony B Pinkerton

Thomas D Y Chung

P577

2017-02-28T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28244987

http://www.w3.org/2001/XMLSchema#string

P932

5570473

http://www.w3.org/2001/XMLSchema#string