Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11 - Test2 - elhamkhani - TriplyDB

Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11

Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11

http://www.wikidata.org/entity/Q27681666

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Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome Substrate specificity of the ubiquitin and Ubl proteases Deubiquitinating enzymes in cellular signaling and disease regulation Targeted inhibition of the deubiquitinating enzymes, USP14 and UCHL5, induces proteotoxic stress and apoptosis in Waldenström macroglobulinaemia tumour cells Crystal structure of the human COP9 signalosome Molecular architecture of the 40S⋅eIF1⋅eIF3 translation initiation complex Disassembly of Lys11 and mixed linkage polyubiquitin conjugates provides insights into function of proteasomal deubiquitinases Rpn11 and Ubp6.Proteasome assembly Structural and biochemical characterization of the Cop9 signalosome CSN5/CSN6 heterodimer Solution structure of yeast Rpn9: insights into proteasome lid assembly Nanobodies as Probes for Protein Dynamics in Vitro and in Cells.Nanobodies to Study G Protein-Coupled Receptor Structure and Function.Base-CP proteasome can serve as a platform for stepwise lid formation Substrate degradation by the proteasome: a single-molecule kinetic analysis.Dissecting Fission Yeast Shelterin Interactions via MICro-MS Links Disruption of Shelterin Bridge to Tumorigenesis Gates, Channels, and Switches: Elements of the Proteasome Machine Structural characterization of the interaction of Ubp6 with the 26S proteasome.Sequential ubiquitination and deubiquitination enzymes synchronize the dual sensor and effector functions of TRIM21 Substrate Ubiquitination Controls the Unfolding Ability of the Proteasome.Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function.Atomic structure of the 26S proteasome lid reveals the mechanism of deubiquitinase inhibition.Structure of an endogenous yeast 26S proteasome reveals two major conformational states USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites.Structure of the human 26S proteasome at a resolution of 3.9 Å.Structural basis for dynamic regulation of the human 26S proteasome.Emerging mechanistic insights into AAA complexes regulating proteasomal degradation.Deubiquitinases and the new therapeutic opportunities offered to cancer.Introduction to the Minireview Series on Modern Technologies for In-cell Biochemistry.Structural disorder and its role in proteasomal degradation.Tuning the proteasome to brighten the end of the journey.The devil is in the details: comparison between COP9 signalosome (CSN) and the LID of the 26S proteasome.Polyubiquitin-Photoactivatable Crosslinking Reagents for Mapping Ubiquitin Interactome Identify Rpn1 as a Proteasome Ubiquitin-Associating Subunit.Proteasome Structure and Assembly.Nanobodies As Tools to Understand, Diagnose, and Treat African Trypanosomiasis.Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.Coinhibition of the deubiquitinating enzymes, USP14 and UCHL5, with VLX1570 is lethal to ibrutinib- or bortezomib-resistant Waldenstrom macroglobulinemia tumor cells Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11.Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome.Structural biology: Corralling a protein-degradation regulator.Meddling with Fate: The Proteasomal Deubiquitinating Enzymes.

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Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11

http://www.wikidata.org/entity/Q27681666

description

2014 nî lūn-bûn

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2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2014 թվականի փետրվարին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年论文

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Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11

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Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11

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Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11

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Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11

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Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11

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Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11

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Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11

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Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11

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Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11

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PNAS.1400546111

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Proceedings of the National Academy of Sciences of the United States of America

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Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11

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Andreas Bracher

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Friedrich Förster

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Ganesh Ramnath Pathare

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Han-Jie Zhou

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István Nagy

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Wolfgang Baumeister

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P2860

JAMM: a metalloprotease-like zinc site in the proteasome and signalosome

The crystal structure of the human Mov34 MPN domain reveals a metal-free dimer

Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains

Structure and activity of the N-terminal substrate recognition domains in proteasomal ATPases

Structure of Rpn10 and Its Interactions with Polyubiquitin Chains and the Proteasome Subunit Rpn12

Structural and Thermodynamic Comparison of the Catalytic Domain of AMSH and AMSH-LP: Nearly Identical Fold but Different Stability

Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1

The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together

The crystal structure of the MPN domain from the COP9 signalosome subunit CSN6

Formation of an intricate helical bundle dictates the assembly of the 26S proteasome lid

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2984-2989

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4902825

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10.1073/PNAS.1400546111

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8

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111

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Daniel J. Anderson

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2014-02-25T00:00:00Z

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260154641

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24516147

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crystal structure

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