4beta-hydroxycholesterol as a marker of CYP3A4 inhibition in vivo - effects of itraconazole in man.
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Validation of 4β-hydroxycholesterol and evaluation of other endogenous biomarkers for the assessment of CYP3A activity in healthy subjects4β-Hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans.No impact of vitamin D on the CYP3A biomarker 4β-hydroxycholesterol in patients with abnormal glucose regulation.Evaluation of 6β-hydroxycortisol, 6β-hydroxycortisone, and a combination of the two as endogenous probes for inhibition of CYP3A4 in vivo.miRNA-27b levels are associated with CYP3A activity in vitro and in vivo.4β-hydroxycholesterol correlates with dose but not steady-state concentration of carbamazepine: indication of intestinal CYP3A in biomarker formation?Compartment-specific gene regulation of the CAR inducer efavirenz in vivo.Impact of efavirenz on intestinal metabolism and transport: insights from an interaction study with ezetimibe in healthy volunteers.Significant increase in plasma 4β-hydroxycholesterol concentration in patients after kidney transplantation.The CYP3A biomarker 4β-hydroxycholesterol does not improve tacrolimus dose predictions early after kidney transplantation.Evaluation of 4β-Hydroxycholesterol as a Clinical Biomarker of CYP3A4 Drug Interactions Using a Bayesian Mechanism-Based Pharmacometric Model.Contribution of cholesterol and oxysterols in the physiopathology of cataract: implication for the development of pharmacological treatmentsComparative performance of oral midazolam clearance and plasma 4β-hydroxycholesterol to explain interindividual variability in tacrolimus clearance.4β-Hydroxycholesterol level significantly correlates with steady-state serum concentration of the CYP3A4 substrate quetiapine in psychiatric patients.
P2860
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P2860
4beta-hydroxycholesterol as a marker of CYP3A4 inhibition in vivo - effects of itraconazole in man.
description
2009 nî lūn-bûn
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2009年の論文
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name
4beta-hydroxycholesterol as a ...... ffects of itraconazole in man.
@en
4beta-hydroxycholesterol as a ...... ffects of itraconazole in man.
@nl
type
label
4beta-hydroxycholesterol as a ...... ffects of itraconazole in man.
@en
4beta-hydroxycholesterol as a ...... ffects of itraconazole in man.
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4beta-hydroxycholesterol as a ...... ffects of itraconazole in man.
@en
4beta-hydroxycholesterol as a ...... ffects of itraconazole in man.
@nl
P2093
P1476
4beta-hydroxycholesterol as a ...... ffects of itraconazole in man.
@en
P2093
Lütjohann D
Marinova M
Oldenburg J
Schneider B
von Bergmann K
P304
P577
2009-12-01T00:00:00Z