UHRF1 recruits the histone acetyltransferase Tip60 and controls its expression and activity.
about
Modifiers and Readers of DNA Modifications and Their Impact on Genome Structure, Expression, and Stability in DiseaseEpigenomics of cancer - emerging new conceptsStructural Insight into Coordinated Recognition of Trimethylated Histone H3 Lysine 9 (H3K9me3) by the Plant Homeodomain (PHD) and Tandem Tudor Domain (TTD) of UHRF1 (Ubiquitin-like, Containing PHD and RING Finger Domains, 1) ProteinSignalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancerConserved linker regions and their regulation determine multiple chromatin-binding modes of UHRF1Cooperative DNA and histone binding by Uhrf2 links the two major repressive epigenetic pathwaysRole for transcription factor TFII-I in the suppression of SSeCKS/Gravin/Akap12 transcription by Src.Introduction--Epiphanies in epigenetics.Poly(ADP-ribose) polymerase 1 (PARP1) associates with E3 ubiquitin-protein ligase UHRF1 and modulates UHRF1 biological functionsModulation of chromatin remodelling induced by the freshwater cyanotoxin cylindrospermopsin in human intestinal caco-2 cells.Coordinated chromatin control: structural and functional linkage of DNA and histone methylation.PKC isoforms interact with and phosphorylate DNMT1UHRF1 is a novel diagnostic marker of lung cancer.Down-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer propertiesFrequent SOCS3 and 3OST2 promoter methylation and their epigenetic regulation in endometrial carcinoma.DNA hypomethylation induces a DNA replication-associated cell cycle arrest to block hepatic outgrowth in uhrf1 mutant zebrafish embryosZinc Finger 280B regulates sGCα1 and p53 in prostate cancer cellsDNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination.Negative regulation of the acetyltransferase TIP60-p53 interplay by UHRF1 (ubiquitin-like with PHD and RING finger domains 1).E3 ligase UHRF2 stabilizes the acetyltransferase TIP60 and regulates H3K9ac and H3K14ac via RING finger domain.Molecular coupling of DNA methylation and histone methylation.Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.DNA damage regulates UHRF1 stability via the SCF(β-TrCP) E3 ligase.The epigenetic integrator UHRF1: on the road to become a universal biomarker for cancer.UHRF1 promotes breast cancer progression by suppressing KLF17 expression by hypermethylating its promoterUhrf1 and Dnmt1 are required for development and maintenance of the zebrafish lensDepletion of Uhrf1 inhibits chromosomal DNA replication in Xenopus egg extracts.Interaction of the epigenetic integrator UHRF1 with the MYST domain of TIP60 inside the cell.Thymoquinone challenges UHRF1 to commit auto-ubiquitination: a key event for apoptosis induction in cancer cells.Ubiquitin Regulation: The Histone Modifying Enzyme's Story
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UHRF1 recruits the histone acetyltransferase Tip60 and controls its expression and activity.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
UHRF1 recruits the histone ace ...... s its expression and activity.
@en
UHRF1 recruits the histone ace ...... s its expression and activity.
@nl
type
label
UHRF1 recruits the histone ace ...... s its expression and activity.
@en
UHRF1 recruits the histone ace ...... s its expression and activity.
@nl
prefLabel
UHRF1 recruits the histone ace ...... s its expression and activity.
@en
UHRF1 recruits the histone ace ...... s its expression and activity.
@nl
P2093
P1476
UHRF1 recruits the histone ace ...... ls its expression and activity
@en
P2093
Guy Fuhrmann
Mahmoud Alhosin
Marc Mousli
Mayada Achour
Philippe Rondé
Thierry Chataigneau
Valérie B Schini-Kerth
P304
P356
10.1016/J.BBRC.2009.09.131
P407
P577
2009-10-02T00:00:00Z