Protein purification and function assignment of the epoxidase catalyzing the formation of fosfomycin.
about
An unusual carbon-carbon bond cleavage reaction during phosphinothricin biosynthesisSynthesis of methylphosphonic acid by marine microbes: a source for methane in the aerobic oceanPurification and characterization of the epoxidase catalyzing the formation of fosfomycin from Pseudomonas syringaeDetermination of the substrate binding mode to the active site iron of (S)-2-hydroxypropylphosphonic acid epoxidase using 17O-enriched substrates and substrate analoguesStructural Basis of Regiospecificity of a Mononuclear Iron Enzyme in Antibiotic Fosfomycin BiosynthesisMechanistic studies of an unprecedented enzyme-catalysed 1,2-phosphono-migration reactionMolecular cloning and heterologous expression of the dehydrophos biosynthetic gene clusterEvidence that the fosfomycin-producing epoxidase, HppE, is a non-heme-iron peroxidaseStructural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme.Substrate activation by iron superoxo intermediates.Structure and mechanism of enzymes involved in biosynthesis and breakdown of the phosphonates fosfomycin, dehydrophos, and phosphinothricin.Enzymatic chemistry of cyclopropane, epoxide, and aziridine biosynthesis.Different biosynthetic pathways to fosfomycin in Pseudomonas syringae and Streptomyces species.Mechanistic investigation of methylphosphonate synthase, a non-heme iron-dependent oxygenase.Evidence for radical-mediated catalysis by HppE: a study using cyclopropyl and methylenecyclopropyl substrate analoguesRings, radicals, and regeneration: the early years of a bioorganic laboratoryEndoperoxide formation by an α-ketoglutarate-dependent mononuclear non-haem iron enzymeBiosynthesis of fosfomycin, re-examination and re-confirmation of a unique Fe(II)- and NAD(P)H-dependent epoxidation reaction.Phosphonate biosynthesis and catabolism: a treasure trove of unusual enzymology.Reaction of HppE with substrate analogues: evidence for carbon-phosphorus bond cleavage by a carbocation rearrangement.Biosynthesis of phosphonic and phosphinic acid natural products.Genome mining in Streptomyces avermitilis: A biochemical Baeyer-Villiger reaction and discovery of a new branch of the pentalenolactone family tree.Hydroperoxylation by hydroxyethylphosphonate dioxygenase.18O kinetic isotope effects in non-heme iron enzymes: probing the nature of Fe/O2 intermediates.Characterization of Two Late-Stage Enzymes Involved in Fosfomycin Biosynthesis in Pseudomonads.Mechanistic consequences of chiral radical clock probes: analysis of the mononuclear non-heme iron enzyme HppE with 2-hydroxy-3-methylenecyclopropyl radical clock substrates.Oxidative Cyclization in Natural Product BiosynthesisDioxygen activation by nonheme iron enzymes with the 2-His-1-carboxylate facial triad that generate high-valent oxoiron oxidants.Initial characterization of Fom3 from Streptomyces wedmorensis: The methyltransferase in fosfomycin biosynthesis.Regio- and stereodivergent antibiotic oxidative carbocyclizations catalysed by Rieske oxygenase-like enzymes.On the catalytic mechanism of (S)-2-hydroxypropylphosphonic acid epoxidase (HppE): a hybrid DFT study.Biochemistry: Positive and radical.Structural basis for methylphosphonate biosynthesis.
P2860
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P2860
Protein purification and function assignment of the epoxidase catalyzing the formation of fosfomycin.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Protein purification and funct ...... g the formation of fosfomycin.
@en
Protein purification and funct ...... g the formation of fosfomycin.
@nl
type
label
Protein purification and funct ...... g the formation of fosfomycin.
@en
Protein purification and funct ...... g the formation of fosfomycin.
@nl
prefLabel
Protein purification and funct ...... g the formation of fosfomycin.
@en
Protein purification and funct ...... g the formation of fosfomycin.
@nl
P2093
P356
P1476
Protein purification and funct ...... g the formation of fosfomycin.
@en
P2093
Murakami K
P304
P356
10.1021/JA004153Y
P407
P577
2001-05-01T00:00:00Z