Comparative metabolism of benzo[a]pyrene and drugs in human liver.
about
Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylaminesA genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 allelesMolecular genetics of the human cytochrome P450 monooxygenase superfamilyAntipyrine kinetics in liver disease and liver transplantation.Antipyrine clearance and metabolism in patients with psoriasis.Coumarin 7-hydroxylase activity in human liver microsomes. Properties of the enzyme and interspecies comparisons.Phenotypic CYP2A6 variation and the risk of pancreatic cancer.Phenotyping of cytochromes P-450 in human tissues with monoclonal antibodiesHuman skin aryl hydrocarbon hydroxylase. Induction by coal tar.The use of human liver for foreign compound metabolism and toxicity studies.Disposition of hexobarbital: 15 years of an intriguing model substrate.Studies on the different metabolic pathways of antipyrine in rats: influence of phenobarbital and 3-methylcholanthrene treatment.Disease as one of many variables affecting drug disposition and response: alterations of drug disposition in liver disease.Studies on the metabolism of benzo[a]pyrene and dose-dependent differences in the mutagenic profile of its ultimate carcinogenic metabolite.Genetic polymorphisms in human drug-metabolizing enzymes: potential uses of reverse genetics to identify genes of toxicological relevance.Antipyrine clearance and metabolite formation: the influence of liver volume and smoking.A comparative study of antipyrine and lignocaine disposition in normal subjects and in patients treated with enzyme-inducing drugs.Genetic predisposition to lung cancerAttempts to phenotype human liver samples in vitro for debrisoquine 4-hydroxylase activity.Determination of cytochrome P-448 activity in biological tissues.Monooxygenase activity of human liver in microsomal fractions of needle biopsy specimens.Differences in metabolism of chemical carcinogens in cultured human epithelial tissues and cells.Correlation between the metabolism of hexobarbital and aminopyrine in vivo in rats.
P2860
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P2860
Comparative metabolism of benzo[a]pyrene and drugs in human liver.
description
1977 nî lūn-bûn
@nan
1977年の論文
@ja
1977年学术文章
@wuu
1977年学术文章
@zh
1977年学术文章
@zh-cn
1977年学术文章
@zh-hans
1977年学术文章
@zh-my
1977年学术文章
@zh-sg
1977年學術文章
@yue
1977年學術文章
@zh-hant
name
Comparative metabolism of benzo[a]pyrene and drugs in human liver.
@en
Comparative metabolism of benzo[a]pyrene and drugs in human liver.
@nl
type
label
Comparative metabolism of benzo[a]pyrene and drugs in human liver.
@en
Comparative metabolism of benzo[a]pyrene and drugs in human liver.
@nl
prefLabel
Comparative metabolism of benzo[a]pyrene and drugs in human liver.
@en
Comparative metabolism of benzo[a]pyrene and drugs in human liver.
@nl
P2093
P356
P1476
Comparative metabolism of benzo[a]pyrene and drugs in human liver.
@en
P2093
Kapitulnik J
P304
P356
10.1002/CPT1977212166
P407
P577
1977-02-01T00:00:00Z