DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV-1 infection of macrophages.
about
SAMHD1: Recurring roles in cell cycle, viral restriction, cancer, and innate immunity.DNA damage induces a SAMHD1-mediated block to the infection of macrophages by HIV-1.The aryl hydrocarbon receptor and interferon gamma generate antiviral states via transcriptional repressionPJA1 Coordinates with the SMC5/6 Complex to Restrict DNA Viruses and Episomal Genes through Interferon-independent Manner
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DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV-1 infection of macrophages.
description
2017 nî lūn-bûn
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name
DNA damage induced by topoisom ...... IV-1 infection of macrophages.
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DNA damage induced by topoisom ...... IV-1 infection of macrophages.
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type
label
DNA damage induced by topoisom ...... IV-1 infection of macrophages.
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DNA damage induced by topoisom ...... IV-1 infection of macrophages.
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prefLabel
DNA damage induced by topoisom ...... IV-1 infection of macrophages.
@en
DNA damage induced by topoisom ...... IV-1 infection of macrophages.
@nl
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DNA damage induced by topoisom ...... IV-1 infection of macrophages.
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Ian A Taylor
Sarah J Caswell
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10.15252/EMBJ.201796880
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2017-10-30T00:00:00Z