Rho kinase inhibition modulates microglia activation and improves survival in a model of amyotrophic lateral sclerosis.
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Cellular and Molecular Mechanisms Underpinning Macrophage Activation during RemyelinationEmerging preclinical pharmacological targets for Parkinson's diseaseEmerging Roles of Filopodia and Dendritic Spines in Motoneuron Plasticity during Development and DiseaseNon-muscle myosin II in disease: mechanisms and therapeutic opportunitiesRho family GTPases: key players in neuronal development, neuronal survival, and neurodegenerationMicroglia processes associate with diffusely injured axons following mild traumatic brain injury in the micro pig.Rac1 at the crossroad of actin dynamics and neuroinflammation in Amyotrophic Lateral Sclerosis.The rho kinase inhibitor Y-27632 improves motor performance in male SOD1(G93A) mice.Neurotrophic requirements of human motor neurons defined using amplified and purified stem cell-derived cultures.Transcriptomic analysis and 3D bioengineering of astrocytes indicate ROCK inhibition produces cytotrophic astrogliosis.Detrimental effect of post Status Epilepticus treatment with ROCK inhibitor Y-27632 in a pilocarpine model of temporal lobe epilepsy.Fasudil attenuates aggregation of α-synuclein in models of Parkinson's diseaseRho Kinase Inhibition with Fasudil in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis-Symptomatic Treatment Potential after Disease Onset.Rho Kinase and Dopaminergic Degeneration: A Promising Therapeutic Target for Parkinson's Disease.Chatting with the neighbors: crosstalk between Rho-kinase (ROCK) and other signaling pathways for treatment of neurological disorders.Modulation of Microglial Activity by Rho-Kinase (ROCK) Inhibition as Therapeutic Strategy in Parkinson's Disease and Amyotrophic Lateral Sclerosis.Interaction between NADPH-oxidase and Rho-kinase in angiotensin II-induced microglial activation.Role of Microglia in Neurological Disorders and Their Potentials as a Therapeutic Target.Altered Expression of Growth Associated Protein-43 and Rho Kinase in Human Patients with Parkinson's Disease.AAV-mediated expression of BAG1 and ROCK2-shRNA promote neuronal survival and axonal sprouting in a rat model of rubrospinal tract injury.Rho kinase inhibition by fasudil in the striatal 6-hydroxydopamine lesion mouse model of Parkinson disease.Increased levels of MIP-1α in CSF and serum of ALS.Tyrphostin AG126 exerts neuroprotection in CNS inflammation by a dual mechanism.Interventions Targeting Glucocorticoid-Krüppel-like Factor 15-Branched-Chain Amino Acid Signaling Improve Disease Phenotypes in Spinal Muscular Atrophy Mice.
P2860
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P2860
Rho kinase inhibition modulates microglia activation and improves survival in a model of amyotrophic lateral sclerosis.
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
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name
Rho kinase inhibition modulate ...... amyotrophic lateral sclerosis.
@en
Rho kinase inhibition modulate ...... amyotrophic lateral sclerosis.
@nl
type
label
Rho kinase inhibition modulate ...... amyotrophic lateral sclerosis.
@en
Rho kinase inhibition modulate ...... amyotrophic lateral sclerosis.
@nl
prefLabel
Rho kinase inhibition modulate ...... amyotrophic lateral sclerosis.
@en
Rho kinase inhibition modulate ...... amyotrophic lateral sclerosis.
@nl
P2093
P2860
P50
P921
P356
P1433
P1476
Rho kinase inhibition modulate ...... amyotrophic lateral sclerosis
@en
P2093
Alexander A Götz
Alexander Balck
Bernhard K Mueller
Elisabeth Barski
Jochen H Weishaupt
Johannes Jansen
Kim-Ann Saal
Martin Suhr
Mathias Bähr
Michael W Sereda
P2860
P304
P356
10.1002/GLIA.22601
P577
2013-12-06T00:00:00Z