Ultrastructure of paired helical filaments of Alzheimer's neurofibrillary tangle.

Ultrastructure of paired helical filaments of Alzheimer's neurofibrillary tangle.

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http://www.wikidata.org/entity/Q48603477
Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filamentsPolymerization of hyperphosphorylated tau into filaments eliminates its inhibitory activity.Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degenerationRole of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer diseaseX-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer disease indicates cross-beta conformation.Purification, ultrastructure, and chemical analysis of Alzheimer disease amyloid plaque core protein.Atomic force microscopy of paired helical filaments isolated from the autopsied brains of patients with Alzheimer's disease and immunolabeled against microtubule-associated protein tau.Immune electron microscopic characterization of monoclonal antibodies to Alzheimer neurofibrillary tangles.Abnormal phosphorylation of tau and the mechanism of Alzheimer neurofibrillary degeneration: sequestration of microtubule-associated proteins 1 and 2 and the disassembly of microtubules by the abnormal tauTwisted ribbon structure of paired helical filaments revealed by atomic force microscopy.Aberrant neurofilament phosphorylation in Alzheimer disease.Image reconstruction of the Alzheimer paired helical filament.Subunit structure of paired helical filaments in Alzheimer's diseaseIntracellular neurofibrillary tangle-like aggregations. A constantly present amyloid alteration in the aging choroid plexus.Alzheimer's paired helical filaments share epitopes with neurofilament side armsTwisted tubulofilaments of inclusion body myositis muscle resemble paired helical filaments of Alzheimer brain and contain hyperphosphorylated tau.
P2860

Ultrastructure of paired helical filaments of Alzheimer's neurofibrillary tangle.

Item
http://www.wikidata.org/entity/Q48603477
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年学术文章
@wuu
1984年学术文章
@zh
1984年学术文章
@zh-cn
1984年学术文章
@zh-hans
1984年学术文章
@zh-my
1984年学术文章
@zh-sg
1984年學術文章
@yue
1984年學術文章
@zh-hant
name
Ultrastructure of paired helical filaments of Alzheimer's neurofibrillary tangle.
@en
Ultrastructure of paired helical filaments of Alzheimer's neurofibrillary tangle.
@nl
type
label
Ultrastructure of paired helical filaments of Alzheimer's neurofibrillary tangle.
@en
Ultrastructure of paired helical filaments of Alzheimer's neurofibrillary tangle.
@nl
prefLabel
Ultrastructure of paired helical filaments of Alzheimer's neurofibrillary tangle.
@en
Ultrastructure of paired helical filaments of Alzheimer's neurofibrillary tangle.
@nl
P1433
P1476
P2093
P304
P31
P433
P478
P577
P698
P921
P1433
P1476
Ultrastructure of paired helical filaments of Alzheimer's neurofibrillary tangle.
@en
P2093
P304
P31
P433
P478
P577
P698
P921