Toward drug repurposing in epigenetics: olsalazine as a hypomethylating compound active in a cellular context.
about
Data-driven approaches used for compound library design, hit triage and bioactivity modeling in high-throughput screening.Rationalization of activity cliffs of a sulfonamide inhibitor of DNA methyltransferases with induced-fit docking.Activity and property landscape modeling is at the interface of chemoinformatics and medicinal chemistry.Activity landscape of DNA methyltransferase inhibitors bridges chemoinformatics with epigenetic drug discovery.Developmental DNA methyltransferase inhibitors in the treatment of gynecologic cancers.Exploring the epigenetic drug discovery landscape.Resveratrol-salicylate derivatives as selective DNMT3 inhibitors and anticancer agents.Systematic analyses of drugs and disease indications in RepurposeDB reveal pharmacological, biological and epidemiological factors influencing drug repositioning.Drug Metabolism in Preclinical Drug Development: A Survey of the Discovery Process, Toxicology, and Computational Tools.Chemoinformatics: a perspective from an academic setting in Latin America.A chemical space odyssey of inhibitors of histone deacetylases and bromodomains
P2860
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P2860
Toward drug repurposing in epigenetics: olsalazine as a hypomethylating compound active in a cellular context.
description
2014 nî lūn-bûn
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2014年の論文
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name
Toward drug repurposing in epi ...... active in a cellular context.
@en
Toward drug repurposing in epi ...... active in a cellular context.
@nl
type
label
Toward drug repurposing in epi ...... active in a cellular context.
@en
Toward drug repurposing in epi ...... active in a cellular context.
@nl
prefLabel
Toward drug repurposing in epi ...... active in a cellular context.
@en
Toward drug repurposing in epi ...... active in a cellular context.
@nl
P2093
P2860
P356
P1433
P1476
Toward drug repurposing in epi ...... active in a cellular context.
@en
P2093
Jeremy Tran
José L Medina-Franco
Mark Muller
Nathalie Meurice
P2860
P304
P356
10.1002/CMDC.201300555
P577
2014-01-31T00:00:00Z