Molecular modeling studies of the novel inhibitors of DNA methyltransferases SGI-1027 and CBC12: implications for the mechanism of inhibition of DNMTs
about
Properly substituted analogues of BIX-01294 lose inhibition of G9a histone methyltransferase and gain selective anti-DNA methyltransferase 3A activity.The Cell Shape-determining Csd6 Protein from Helicobacter pylori Constitutes a New Family of L,D-Carboxypeptidase.Design, synthesis and biological evaluation of 4-amino-N- (4-aminophenyl)benzamide analogues of quinoline-based SGI-1027 as inhibitors of DNA methylation.Rationalization of activity cliffs of a sulfonamide inhibitor of DNA methyltransferases with induced-fit docking.Role of computer-aided drug design in modern drug discovery.Resveratrol-salicylate derivatives as selective DNMT3 inhibitors and anticancer agents.DNA methyltransferase inhibitors: an updated patent review (2012-2015).DNA Methyltransferase Inhibitors: Development and Applications.Oct4 Methylation-Mediated Silencing As an Epigenetic Barrier Preventing Müller Glia Dedifferentiation in a Murine Model of Retinal Injury.Toward drug repurposing in epigenetics: olsalazine as a hypomethylating compound active in a cellular context.Establishment of a high-throughput detection system for DNA demethylating agents.
P2860
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P2860
Molecular modeling studies of the novel inhibitors of DNA methyltransferases SGI-1027 and CBC12: implications for the mechanism of inhibition of DNMTs
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Molecular modeling studies of ...... chanism of inhibition of DNMTs
@ast
Molecular modeling studies of ...... chanism of inhibition of DNMTs
@en
Molecular modeling studies of ...... chanism of inhibition of DNMTs
@nl
type
label
Molecular modeling studies of ...... chanism of inhibition of DNMTs
@ast
Molecular modeling studies of ...... chanism of inhibition of DNMTs
@en
Molecular modeling studies of ...... chanism of inhibition of DNMTs
@nl
prefLabel
Molecular modeling studies of ...... chanism of inhibition of DNMTs
@ast
Molecular modeling studies of ...... chanism of inhibition of DNMTs
@en
Molecular modeling studies of ...... chanism of inhibition of DNMTs
@nl
P2860
P3181
P1433
P1476
Molecular modeling studies of ...... chanism of inhibition of DNMTs
@en
P2093
Jakyung Yoo
José L Medina-Franco
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0062152
P407
P50
P577
2013-01-01T00:00:00Z