USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation

about

USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation

Item

http://www.wikidata.org/entity/Q58749340

description

im Oktober 2018 veröffentlichter wissenschaftlicher Artikel

@de

wetenschappelijk artikel

@nl

наукова стаття, опублікована в жовтні 2018

@uk

name

USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation

@en

USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation

@nl

type

Item

label

USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation

@en

USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation

@nl

prefLabel

USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation

@en

USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation

@nl

P1476

USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation

@en

P2093

Ana Valera

http://www.w3.org/2001/XMLSchema#string

Carolina Pellegrini

http://www.w3.org/2001/XMLSchema#string

Fatima Martín-Sánchez

http://www.w3.org/2001/XMLSchema#string

Jonathan D Worboys

http://www.w3.org/2001/XMLSchema#string

P2860

USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA polymerase β

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.

The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

Cytotoxicity of crystals involves RIPK3-MLKL-mediated necroptosis

Deubiquitinases: Novel Therapeutic Targets in Immune Surveillance?

The PYRIN-CARD protein ASC is an activating adaptor for caspase-1

Innate immune pattern recognition: a cell biological perspective

P304

e44766

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.15252/EMBR.201744766

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

David Brough

Gloria López-Castejón

Pablo Palazon-Riquelme

Jack Green

P577

2018-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

30206189

http://www.w3.org/2001/XMLSchema#string

P921

inflammasome

molecular biology

P932

6172458

http://www.w3.org/2001/XMLSchema#string