about
A critical role for the transcription factor Scl in platelet production during stress thrombopoiesisAdaptor protein SKAP55R is associated with myeloid differentiation and growth arrestThe critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12SCL is required for normal function of short-term repopulating hematopoietic stem cellsAberrant mast-cell differentiation in mice lacking the stem-cell leukemia genePerturbed thymopoiesis in vitro in the absence of suppressor of cytokine signalling 1 and 3.Underestimation of myelodysplastic syndrome incidence by cancer registries: Results from a population-based data linkage study.ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling.Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndromeNovel roles for erythroid Ankyrin-1 revealed through an ENU-induced null mouse mutant.PUMA promotes apoptosis of hematopoietic progenitors driving leukemic progression in a mouse model of myelodysplasia.PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing.The fusion partner specifies the oncogenic potential of NUP98 fusion proteinsThe molecular basis of Lmo2-induced T-cell acute lymphoblastic leukemia.Concise review: Blood relatives: formation and regulation of hematopoietic stem cells by the basic helix-loop-helix transcription factors stem cell leukemia and lymphoblastic leukemia-derived sequence 1.LIM-domain-only proteins in cancer.The clonal evolution of leukemic stem cells in T-cell acute lymphoblastic leukemia.The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal.The generation and properties of human macrophage populations from hemopoietic stem cells.Acute myeloid leukaemia relapsing after allogeneic haematopoietic stem cell transplantation: prognostic factors and impact of initial therapy of relapse.Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia.Requirement for Lyl1 in a model of Lmo2-driven early T-cell precursor ALL.Monosomal karyotype predicts inferior survival independently of a complex karyotype in patients with myelodysplastic syndromes.Parvovirus B19 in HIV infection: a treatable cause of anemia.A mouse model of hereditary coproporphyria identified in an ENU mutagenesis screenFunctional but abnormal adult erythropoiesis in the absence of the stem cell leukemia geneSafe and effective use of outpatient non-myeloablative allogeneic stem cell transplantation for myelomaCyclosporin, methotrexate and prednisolone for graft-versus-host disease prophylaxis in allogeneic peripheral blood progenitor cell transplants.Bone marrow cells play only a very minor role in chronic liver regeneration induced by a choline-deficient, ethionine-supplemented diet.The Hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms.Specification of neurotransmitter identity by Tal1 in thalamic nuclei.Activation of the erythroid K-Cl cotransporter Kcc1 enhances sickle cell disease pathology in a humanized mouse model.Loss of Dynamin 2 GTPase function results in microcytic anaemia.Leptin-deficient obesity prolongs survival in a murine model of myelodysplastic syndrome.ENU mutagenesis identifies the first mouse mutants reproducing human β-thalassemia at the genomic level.The CD2-scl transgene alters the phenotype and frequency of T-lymphomas in N-ras transgenic or p53 deficient mice.Adverse impact of high donor CD3+ cell dose on outcome following tandem auto-NMA allogeneic transplantation for high-risk myeloma.Loss-of-function mutations of Dynamin 2 promote T-ALL by enhancing IL-7 signalling.The thymus under siege: Lmo2 induces precancerous stem cells in a mouse model of T-ALL.Comparison of biosimilar filgrastim with originator filgrastim for peripheral blood stem cell mobilization and engraftment in patients with multiple myeloma undergoing autologous stem cell transplantation.
P50
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P50
description
researcher ORCID ID = 0000-0001-9497-0996
@en
name
David J Curtis
@ast
David J Curtis
@en
David J Curtis
@nl
type
label
David J Curtis
@ast
David J Curtis
@en
David J Curtis
@nl
prefLabel
David J Curtis
@ast
David J Curtis
@en
David J Curtis
@nl
P21
P31
P496
0000-0001-9497-0996