about
The full genome sequence of three strains of Jamestown Canyon virus and their pathogenesis in mice or monkeysMechanism and significance of cell type-dependent neutralization of flavivirusesVaccine candidates derived from a novel infectious cDNA clone of an American genotype dengue virus type 2A full-length infectious cDNA clone of Zika virus from the 2015 epidemic in Brazil as a genetic platform for studies of virus-host interactions and vaccine developmentRecombinant, live-attenuated tetravalent dengue virus vaccine formulations induce a balanced, broad, and protective neutralizing antibody response against each of the four serotypes in rhesus monkeys.Paired charge-to-alanine mutagenesis of dengue virus type 4 NS5 generates mutants with temperature-sensitive, host range, and mouse attenuation phenotypes.A Live, Attenuated Dengue Virus Type 1 Vaccine Candidate with a 30-Nucleotide Deletion in the 3' Untranslated Region Is Highly Attenuated and Immunogenic in MonkeysVaccine candidates for dengue virus type 1 (DEN1) generated by replacement of the structural genes of rDEN4 and rDEN4Delta30 with those of DEN1Genome sequence analysis of La Crosse virus and in vitro and in vivo phenotypesDengue virus type 3 vaccine candidates generated by introduction of deletions in the 3′ untranslated region (3′-UTR) or by exchange of the DENV-3 3′-UTR with that of DENV-4Evaluation of the Langat/dengue 4 chimeric virus as a live attenuated tick-borne encephalitis vaccine for safety and immunogenicity in healthy adult volunteersSuperior infectivity for mosquito vectors contributes to competitive displacement among strains of dengue virusLa Crosse virus infectivity, pathogenesis, and immunogenicity in mice and monkeysMaturation of West Nile Virus Modulates Sensitivity to Antibody-Mediated NeutralizationEvaluation of St. Louis encephalitis virus/dengue virus type 4 antigenic chimeric viruses in mice and rhesus monkeysPhase I clinical evaluation of rDEN4Delta30-200,201: a live attenuated dengue 4 vaccine candidate designed for decreased hepatotoxicityPhase 1 Trial of the Dengue Virus Type 4 Vaccine Candidate rDEN4 30-4995 in Healthy Adult VolunteersClinical and Virological Features of Dengue in Vietnamese InfantsDengue research opportunities in the AmericasPatterns of cellular immunity associated with experimental infection with rDEN2Δ30 (Tonga/74) supports its suitability as a human DENV challenge strainHuman CD4+ T cell responses to an attenuated tetravalent dengue vaccine parallel those induced by natural infection, in magnitude, HLA restriction and antigen specificityIn a randomized trial, the live attenuated tetravalent dengue vaccine TV003 is well-tolerated and highly immunogenic in subjects with flavivirus exposure prior to vaccinationGenetically modified, live attenuated dengue virus type 3 vaccine candidates.Investigation of dengue and Japanese encephalitis virus transmission in Hanam, Viet Nam.A human inferred germline antibody binds to an immunodominant epitope and neutralizes Zika virus.Japanese encephalitis virus vaccine candidates generated by chimerization with dengue virus type 4A dynamic landscape for antibody binding modulates antibody-mediated neutralization of West Nile virusA single dose of the DENV-1 candidate vaccine rDEN1Δ30 is strongly immunogenic and induces resistance to a second dose in a randomized trial.Report of an NIAID workshop on dengue animal models.A novel approach for the rapid mutagenesis and directed evolution of the structural genes of west nile virusTahyna virus genetics, infectivity, and immunogenicity in mice and monkeys.Infection dynamics of sylvatic dengue virus in a natural primate host, the African Green Monkey.Primary vaccination with low dose live dengue 1 virus generates a proinflammatory, multifunctional T cell response in humans.Heterotypic dengue infection with live attenuated monotypic dengue virus vaccines: implications for vaccination of populations in areas where dengue is endemic.The human CD8+ T cell responses induced by a live attenuated tetravalent dengue vaccine are directed against highly conserved epitopes.The type-specific neutralizing antibody response elicited by a dengue vaccine candidate is focused on two amino acids of the envelope protein.Corticosteroids for dengue - why don't they work?Replacement of the 3' untranslated variable region of mosquito-borne dengue virus with that of tick-borne Langat virus does not alter vector specificity.Dengue virus infections and maternal antibody decay in a prospective birth cohort study of Vietnamese infants.Genetic and phenotypic properties of vero cell-adapted Japanese encephalitis virus SA14-14-2 vaccine strain variants and a recombinant clone, which demonstrates attenuation and immunogenicity in mice.
P50
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P50
name
Stephen S Whitehead
@ast
Stephen S Whitehead
@en
Stephen S Whitehead
@nl
type
label
Stephen S Whitehead
@ast
Stephen S Whitehead
@en
Stephen S Whitehead
@nl
prefLabel
Stephen S Whitehead
@ast
Stephen S Whitehead
@en
Stephen S Whitehead
@nl