about
sameAs
P688
Human exonuclease I interacts with the mismatch repair protein hMSH2Identification of factors interacting with hMSH2 in the fetal liver utilizing the yeast two-hybrid system. In vivo interaction through the C-terminal domains of hEXO1 and hMSH2 and comparative expression analysisThe interaction of DNA mismatch repair proteins with human exonuclease IHNPCC mutations in the human DNA mismatch repair gene hMLH1 influence assembly of hMutLalpha and hMLH1-hEXO1 complexesFunctional analysis of human MLH1 and MSH2 missense variants and hybrid human-yeast MLH1 proteins in Saccharomyces cerevisiaeActivation of human MutS homologs by 8-oxo-guanine DNA damageHuman MutY homolog, a DNA glycosylase involved in base excision repair, physically and functionally interacts with mismatch repair proteins human MutS homolog 2/human MutS homolog 6hMutSalpha forms an ATP-dependent complex with hMutLalpha and hMutLbeta on DNA.Interactions between p53, hMSH2-hMSH6 and HMG I(Y) on Holliday junctions and bulged basesTranscription promotes contraction of CAG repeat tracts in human cellsAnalysis of the human MutLalpha.MutSalpha complexMSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylationCharacterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNAFunctional and physical interactions between ERCC1 and MSH2 complexes for resistance to cis-diamminedichloroplatinum(II) in mammalian cellsFunctional alterations of human exonuclease 1 mutants identified in atypical hereditary nonpolyposis colorectal cancer syndromePurified human MSH2 protein binds to DNA containing mismatched nucleotideshMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adductsDifferential specificities and simultaneous occupancy of human MutSalpha nucleotide binding sitesPhysical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factorsRibonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repairThe histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSαMCM9 Is Required for Mammalian DNA Mismatch Repair.
P921
Q50253831-632516BB-F4B9-4820-9425-C699D6470526Q50253837-7D256F11-2A07-4EE6-B4D0-527FFDFAC7E2Q50253848-3CFDF3AB-FFE3-413B-AE49-0B94ABEB8CC0Q50253853-276C9C8B-E689-410E-BE16-5D3300027279Q50257085-921B60EC-B206-484A-B596-90D166BC2D70Q50287450-B8ACCF7D-28A1-4458-A04A-1F16C74A7BD8Q50287461-7A2D31A8-DE6B-48ED-91B0-B63357253FF4Q50289711-8CBD2603-6AF5-4823-829C-4972499287B1Q50289712-6513DD7A-3B2E-4B99-8806-1FDA46E94B42Q50290297-16177CC0-CD7A-4D4F-B755-DC233CF07C25
P527
description
humanes Protein
@de
mammalian protein found in Homo sapiens
@en
menselijk eiwit
@nl
protein
@id
protein
@sv
proteinë
@sq
protèin
@ace
protéine humaine
@fr
بروتين بشري
@ar
name
MSH2
@es
MSH2
@pl
MutS homolog 2
@en
MutS homolog 2
@nl
type
label
MSH2
@es
MSH2
@pl
MutS homolog 2
@en
MutS homolog 2
@nl
altLabel
DNA mismatch repair protein Msh2 transcript
@en
DNA mismatch repair protein Msh2
@en
HMSH2
@pl
MSH2
@en
MutS protein homolog 2
@en
hMSH2
@en
mutS homolog 2, colon cancer, nonpolyposis type 1
@en
prefLabel
MSH2
@es
MSH2
@pl
MutS homolog 2
@en
MutS homolog 2
@nl
P361
P527
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P705
P352
P486
P31
P352
P361
P486
P527
P637
NP_001245210
XP_005264389
XP_011531169
P638
P680
P681
P682
P702
P703
P705
ENSP00000233146
ENSP00000384199
ENSP00000442697
ENSP00000495455
ENSP00000495543
ENSP00000495641
ENSP00000496351
ENSP00000496441