The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer
about
Pin1 and WWP2 regulate GluR2 Q/R site RNA editing by ADAR2 with opposing effectsNotch Signaling in Neuroendocrine TumorsProlyl isomerase Pin1 in cancerThe CSL proteins, versatile transcription factors and context dependent corepressors of the notch signaling pathwayUnderstanding the role of PIN1 in hepatocellular carcinomaKSHV reactivation and novel implications of protein isomerization on lytic switch controlLandscape of Pin1 in the cell cycleRegulation of cardiac hypertrophic signaling by prolyl isomerase Pin1Prolyl isomerase Pin1 regulates neuronal differentiation via β-cateninBCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targetsA Presenilin-2-ARF4 trafficking axis modulates Notch signaling during epidermal differentiationPin1 promotes transforming growth factor-beta-induced migration and invasion.Dynamic regulation of Pin1 expression and function during zebrafish development.Pin1 facilitates the phosphorylation-dependent ubiquitination of SF-1 to regulate gonadotropin beta-subunit gene transcriptionA covalent PIN1 inhibitor selectively targets cancer cells by a dual mechanism of action.Stochastic simulation of notch signaling reveals novel factors that mediate the differentiation of neural stem cells.Prolyl isomerase Pin1 regulates mouse embryonic fibroblast differentiation into adipose cells.The roles of peptidyl-proline isomerases in gene regulation.Proline isomerase Pin1 represses terminal differentiation and myocyte enhancer factor 2C function in skeletal muscle cells.Notch inhibitors for cancer treatment.Notch signaling in pediatric soft tissue sarcomasHigh throughput kinase inhibitor screens reveal TRB3 and MAPK-ERK/TGFβ pathways as fundamental Notch regulators in breast cancer.Loss of Pin1 Suppresses Hedgehog-Driven Medulloblastoma Tumorigenesis.Pin1-mediated Sp1 phosphorylation by CDK1 increases Sp1 stability and decreases its DNA-binding activity during mitosis.Pin1 regulates the dynamics of c-Myc DNA binding to facilitate target gene regulation and oncogenesis.Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular functionUXT potentiates angiogenesis by attenuating Notch signaling.Late SV40 factor: a key mediator of Notch signaling in human hepatocarcinogenesis.Hierarchical phosphorylation within the ankyrin repeat domain defines a phosphoregulatory loop that regulates Notch transcriptional activityProlyl isomerases in gene transcriptionCyclosporin a disrupts notch signaling and vascular lumen maintenance.D,L-sulforaphane-induced apoptosis in human breast cancer cells is regulated by the adapter protein p66Shc.All-trans-retinoic Acid Modulates the Plasticity and Inhibits the Motility of Breast Cancer Cells: ROLE OF NOTCH1 AND TRANSFORMING GROWTH FACTOR (TGFβ).Defining NOTCH3 target genes in ovarian cancer.Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase.Prolyl isomerase Pin1 downregulates tumor suppressor RUNX3 in breast cancer.Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cellsPeptidyl-prolyl cis/trans-isomerase A1 (Pin1) is a target for modification by lipid electrophiles.Notch1 hallmarks fibrillary depositions in sporadic Alzheimer's disease.NOTCH1 Inhibits Activation of ATM by Impairing the Formation of an ATM-FOXO3a-KAT5/Tip60 Complex.
P2860
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P2860
The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer
@ast
The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer
@en
The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer
@en-gb
The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer
@nl
type
label
The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer
@ast
The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer
@en
The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer
@en-gb
The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer
@nl
prefLabel
The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer
@ast
The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer
@en
The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer
@en-gb
The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer
@en
P2093
Alessandra Rustighi
Anthony Capobianco
Fred Kaplan
Salvatore Pece
P2860
P2888
P304
P3181
P356
10.1038/NCB1822
P407
P50
P577
2009-02-01T00:00:00Z
P5875
P6179
1005991297