Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC)
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Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retinaTowards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesGenetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degenerationAMD Genetics in India: The Missing LinksAMD and the alternative complement pathway: genetics and functional implicationsGenetics of immunological and inflammatory components in age-related macular degenerationAdvances in the genomics of common eye diseasesGenetic and environmental underpinnings to age-related ocular diseasesDifferential modulation of retinal degeneration by Ccl2 and Cx3cr1 chemokine signallingThe lipid translocase, ABCA4: seeing is believing.Macular xanthophylls, lipoprotein-related genes, and age-related macular degenerationGenome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk lociImpaired cholesterol efflux in senescent macrophages promotes age-related macular degenerationGenetic determinants of age-related macular degeneration in diverse populations from the PAGE studySpatial distribution of the pathways of cholesterol homeostasis in human retinaElevated high-density lipoprotein cholesterol and age-related macular degeneration: the Alienor studyUsing genetic variation and environmental risk factor data to identify individuals at high risk for age-related macular degenerationGenetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysisHeritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypesSeven new loci associated with age-related macular degeneration.Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3Epidemiology of age-related macular degeneration (AMD): associations with cardiovascular disease phenotypes and lipid factors.Abnormal vascularization in mouse retina with dysregulated retinal cholesterol homeostasis.Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular diseaseMeta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraineTowards finding the linkage between metabolic and age-related disorders using semantic gene data network analysisAssociation of HDL-related loci with age-related macular degeneration and plasma lutein and zeaxanthin: the Alienor study.Genetic risk, ethnic variations and pharmacogenetic biomarkers in age-related macular degeneration and polypoidal choroidal vasculopathyThe oxysterol 27-hydroxycholesterol increases β-amyloid and oxidative stress in retinal pigment epithelial cells.Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function.Cholesterol in the retina: the best is yet to come.Why AMD is a disease of ageing and not of development: mechanisms and insights.Identifying subtypes of patients with neovascular age-related macular degeneration by genotypic and cardiovascular risk characteristics.Age-related macular degeneration-associated variants at chromosome 10q26 do not significantly alter ARMS2 and HTRA1 transcript levels in the human retina.Lipids, lipid genes, and incident age-related macular degeneration: the three continent age-related macular degeneration consortiumGene ontology and KEGG enrichment analyses of genes related to age-related macular degeneration.Cholesterol oxidation in the retina: implications of 7KCh formation in chronic inflammation and age-related macular degenerationModelling the genetic risk in age-related macular degeneration.Bioactive lysophospholipids generated by hepatic lipase degradation of lipoproteins lead to complement activation via the classical pathway
P2860
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P2860
Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC)
description
2010 nî lūn-bûn
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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2010 թվականի ապրիլին հրատարակված գիտական հոդված
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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name
Genome-wide association study ...... the hepatic lipase gene (LIPC)
@ast
Genome-wide association study ...... the hepatic lipase gene (LIPC)
@en
Genome-wide association study ...... the hepatic lipase gene (LIPC)
@nl
type
label
Genome-wide association study ...... the hepatic lipase gene (LIPC)
@ast
Genome-wide association study ...... the hepatic lipase gene (LIPC)
@en
Genome-wide association study ...... the hepatic lipase gene (LIPC)
@nl
prefLabel
Genome-wide association study ...... the hepatic lipase gene (LIPC)
@ast
Genome-wide association study ...... the hepatic lipase gene (LIPC)
@en
Genome-wide association study ...... the hepatic lipase gene (LIPC)
@nl
P2093
P2860
P50
P3181
P356
P1476
Genome-wide association study ...... the hepatic lipase gene (LIPC)
@en
P2093
Benjamin M Neale
Betsy Campochiaro
Binxing Li
Edwin C Oh
Eric Souied
Gaetano R Barile
Jeanne M Frederick
Jesen Fagerness
Joanna E Merriam
Johanna M Seddon
P2860
P304
P3181
P356
10.1073/PNAS.0912019107
P407
P577
2010-04-12T00:00:00Z