Direct inhibition of the NOTCH transcription factor complex
about
Systematic analysis of helical protein interfaces reveals targets for synthetic inhibitorsDeletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemiaNotch signaling: its roles and therapeutic potential in hematological malignanciesTargeting Notch to overcome radiation resistanceTargeting self-renewal pathways in cancer stem cells: clinical implications for cancer therapyTargeting cancer stem cells by using the nanoparticlesMYC-driven aggressive B-cell lymphomas: biology, entity, differential diagnosis and clinical managementNotch signaling deregulation in multiple myeloma: A rational molecular targetTargeting melanoma by small molecules: challenges aheadImpact of notch signaling on inflammatory responses in cardiovascular disordersEpigenetic regulation of fetal globin gene expression in adult erythroid cellsNotch signaling in prostate cancer: a moving targetExpanding the number of 'druggable' targets: non-enzymes and protein-protein interactionsFrom fly wings to targeted cancer therapies: a centennial for notch signalingNotch regulation of bone development and remodeling and related skeletal disordersGetting in shape: controlling peptide bioactivity and bioavailability using conformational constraintsGain of Olig2 function in oligodendrocyte progenitors promotes remyelination.Plasma Hsp90 Level as a Marker of Early Acute Lymphoblastic Leukemia Engraftment and Progression in MiceT. gondii RP promoters & knockdown reveal molecular pathways associated with proliferation and cell-cycle arrestStapled BH3 peptides against MCL-1: mechanism and design using atomistic simulationsControlled Protein Dimerization through Hybrid Coordination MotifsA Left-Handed Solution to Peptide Inhibition of the p53-MDM2 InteractionD-peptide inhibitors of the p53–MDM2 interaction for targeted molecular therapy of malignant neoplasmsStructural Basis for Cyclic Py-Im Polyamide Allosteric Inhibition of Nuclear Receptor BindingInhibition of oncogenic Wnt signaling through direct targeting of -cateninEvaluation of Diverse α/β-Backbone Patterns for Functional α-Helix Mimicry: Analogues of the Bim BH3 DomainStapled α−helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapyDiscovery of a Potent Stapled Helix Peptide That Binds to the 70N Domain of Replication Protein AOxime side-chain cross-links in an α-helical coiled-coil protein: structure, thermodynamics, and folding-templated synthesis of bicyclic speciesThe relevance of PTEN-AKT in relation to NOTCH1-directed treatment strategies in T-cell acute lymphoblastic leukemiaRSK3: A regulator of pathological cardiac remodelingIdentification of the nuclear localization signal of SALL4B, a stem cell transcription factorTargeting transcription factor SALL4 in acute myeloid leukemia by interrupting its interaction with an epigenetic complexNovel polymeric nanoparticles for intracellular delivery of peptide Cargos: antitumor efficacy of the BCL-2 conversion peptide NuBCP-9Hydrocarbon-stapled peptides: principles, practice, and progressNOTCH1 signaling promotes human T-cell acute lymphoblastic leukemia initiating cell regeneration in supportive nichesPepComposer: computational design of peptides binding to a given protein surfaceOvercoming therapeutic resistance in glioblastoma: the way forwardDevelopment of QSAR-Improved Statistical Potential for the Structure-Based Analysis of ProteinPeptide Binding Affinities.Constraining cyclic peptides to mimic protein structure motifs.
P2860
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P2860
Direct inhibition of the NOTCH transcription factor complex
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Direct inhibition of the NOTCH transcription factor complex
@ast
Direct inhibition of the NOTCH transcription factor complex
@en
Direct inhibition of the NOTCH transcription factor complex
@nl
type
label
Direct inhibition of the NOTCH transcription factor complex
@ast
Direct inhibition of the NOTCH transcription factor complex
@en
Direct inhibition of the NOTCH transcription factor complex
@nl
prefLabel
Direct inhibition of the NOTCH transcription factor complex
@ast
Direct inhibition of the NOTCH transcription factor complex
@en
Direct inhibition of the NOTCH transcription factor complex
@nl
P2093
P2860
P3181
P356
P1433
P1476
Direct inhibition of the NOTCH transcription factor complex
@en
P2093
Cristina Del Bianco
D Gary Gilliland
Gregory L Verdine
James E Bradner
Jon C Aster
Melanie Cornejo
Stephen C Blacklow
Tina N Davis
P2860
P2888
P3181
P356
10.1038/NATURE08543
P407
P577
2009-11-12T00:00:00Z
P5875
P6179
1000625174