The nicotinic acetylcholine receptor: the founding father of the pentameric ligand-gated ion channel superfamily
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Crystal structures of free and antagonist-bound states of human α9 nicotinic receptor extracellular domainThe human CHRNA7 and CHRFAM7A genes: A review of the genetics, regulation, and functionThe concept of allosteric interaction and its consequences for the chemistry of the brainCholinergic modulation of the medial prefrontal cortex: the role of nicotinic receptors in attention and regulation of neuronal activityEscherichia coli Protein Expression System for Acetylcholine Binding Proteins (AChBPs)ABT-089, but not ABT-107, ameliorates nicotine withdrawal-induced cognitive deficits in C57BL6/J mice.Molecular determinants of agonist selectivity in glutamate-gated chloride channels which likely explain the agonist selectivity of the vertebrate glycine and GABAA-ρ receptorsReovirus cell entry requires functional microtubules.The 3,7-diazabicyclo[3.3.1]nonane scaffold for subtype selective nicotinic acetylcholine receptor ligands. Part 2: carboxamide derivatives with different spacer motifs.The 3,7-diazabicyclo[3.3.1]nonane scaffold for subtype selective nicotinic acetylcholine receptor (nAChR) ligands. Part 1: the influence of different hydrogen bond acceptor systems on alkyl and (hetero)aryl substituents.Small changes in bone structure of female α7 nicotinic acetylcholine receptor knockout mice.Marine natural products acting on the acetylcholine-binding protein and nicotinic receptors: from computer modeling to binding studies and electrophysiology.α7 Nicotinic acetylcholine receptor-specific antibody induces inflammation and amyloid β42 accumulation in the mouse brain to impair memory.Allosteric regulation of pentameric ligand-gated ion channels: an emerging mechanistic perspectiveThe synaptotagmin juxtamembrane domain is involved in neuroexocytosis.Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal α7 from Muscle α1(2)βγδ nAChRs.The influence of allosteric modulators and transmembrane mutations on desensitisation and activation of α7 nicotinic acetylcholine receptorsCompetition, Selectivity and Efficacy of Analogs of A-84543 for Nicotinic Acetylcholine Receptors with Repositioning of Pyridine Nitrogen.Microarray-Based Comparisons of Ion Channel Expression Patterns: Human Keratinocytes to Reprogrammed hiPSCs to Differentiated Neuronal and Cardiac Progeny.Mutagenic analysis of the intracellular portals of the human 5-HT3A receptor.Conduits of life's spark: a perspective on ion channel research since the birth of neuron.The energy and work of a ligand-gated ion channel.Photoaffinity labeling of nicotinic receptors: diversity of drug binding sites!Nicotinic cholinergic signaling in adipose tissue and pancreatic islets biology: revisited function and therapeutic perspectives.Chemical crosslinkers enhance detection of receptor interactomes.Mitochondrial channels: ion fluxes and more.Pentameric Ligand-gated Ion Channels : Insights from Computation.Natural compounds interacting with nicotinic acetylcholine receptors: from low-molecular weight ones to peptides and proteins.Discriminative Stimulus Properties of S(-)-Nicotine: "A Drug for All Seasons".A Transcriptomic Survey of Ion Channel-Based Conotoxins in the Chinese Tubular Cone Snail (Conus betulinus).α-Conotoxins active at α3-containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition.Cholinergic modulation of the immune system presents new approaches for treating inflammation.Angiotensin AT1 and AT2 receptor antagonists modulate nicotine-evoked [³H]dopamine and [³H]norepinephrine release.A G protein-coupled α7 nicotinic receptor regulates signaling and TNF-α release in microgliaProtein dynamics and the allosteric transitions of pentameric receptor channels.Structural mechanisms for α-conotoxin activity at the human α3β4 nicotinic acetylcholine receptor.Single nucleotide polymorphisms and genotypes of transient receptor potential ion channel and acetylcholine receptor genes from isolated B lymphocytes in myalgic encephalomyelitis/chronic fatigue syndrome patients.Introduction to thematic minireview series on celebrating the discovery of the cysteine loop ligand-gated ion channel superfamily.Cholinergic Modulation of Cortical Microcircuits Is Layer-Specific: Evidence from Rodent, Monkey and Human Brain.Enantiomeric barbiturates bind distinct inter- and intrasubunit binding sites in a nicotinic acetylcholine receptor (nAChR).
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The nicotinic acetylcholine receptor: the founding father of the pentameric ligand-gated ion channel superfamily
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
The nicotinic acetylcholine re ...... -gated ion channel superfamily
@ast
The nicotinic acetylcholine re ...... -gated ion channel superfamily
@en
The nicotinic acetylcholine re ...... -gated ion channel superfamily
@nl
type
label
The nicotinic acetylcholine re ...... -gated ion channel superfamily
@ast
The nicotinic acetylcholine re ...... -gated ion channel superfamily
@en
The nicotinic acetylcholine re ...... -gated ion channel superfamily
@nl
prefLabel
The nicotinic acetylcholine re ...... -gated ion channel superfamily
@ast
The nicotinic acetylcholine re ...... -gated ion channel superfamily
@en
The nicotinic acetylcholine re ...... -gated ion channel superfamily
@nl
P2860
P3181
P356
P1476
The nicotinic acetylcholine re ...... -gated ion channel superfamily
@en
P2093
J.-P. Changeux
P2860
P304
P3181
P356
10.1074/JBC.R112.407668
P407
P577
2012-11-23T00:00:00Z