Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation
about
Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assemblyA crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.Role of scaffold protein afadin dilute domain-interacting protein (ADIP) in platelet-derived growth factor-induced cell movement by activating Rac protein through Vav2 proteinA mammalian Rho-specific guanine-nucleotide exchange factor (p164-RhoGEF) without a pleckstrin homology domainStructural basis for Rab GTPase activation by VPS9 domain exchange factorsA bacterial effector targets host DH-PH domain RhoGEFs and antagonizes macrophage phagocytosisEphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formationThe tandem BRCT domains of Ect2 are required for both negative and positive regulation of Ect2 in cytokinesisAn ECT2-centralspindlin complex regulates the localization and function of RhoAStructural basis for membrane recruitment and allosteric activation of cytohesin family Arf GTPase exchange factorsCrucial structural role for the PH and C1 domains of the Vav1 exchange factorAsef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation elementOligomerization of DH domain is essential for Dbl-induced transformationGGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteinsActivation of RasGRP3 by phosphorylation of Thr-133 is required for B cell receptor-mediated Ras activationVav2 is required for cell spreadingScambio, a novel guanine nucleotide exchange factor for RhoVav1: A Dr. Jekyll and Mr. Hyde protein--good for the hematopoietic system, bad for cancerPhosphorylation-mediated regulation of GEFs for RhoARho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and diseaseFunction and regulation of the Rho guanine nucleotide exchange factor TrioVav family exchange factors: an integrated regulatory and functional viewStructural Basis and Mechanism of Autoregulation in 3-Phosphoinositide-Dependent Grp1 Family Arf GTPase Exchange FactorsStructural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1The Minimal Autoinhibited Unit of the Guanine Nucleotide Exchange Factor IntersectinRas superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formationVav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducers in T cell antigen receptor-induced pathwaysRegulation of proto-Dbl by intracellular membrane targeting and protein stabilityBasic fibroblast growth factor stimulates activation of Rac1 through a p85 betaPIX phosphorylation-dependent pathwayRegulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinaseStructural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factorCharacterization of the biochemical and transforming properties of the neuroepithelial transforming protein 1Ccpg1, a novel scaffold protein that regulates the activity of the Rho guanine nucleotide exchange factor DbsTyrosine phosphorylation within the intrinsically disordered cytosolic domains of the B-cell receptor: an NMR-based structural analysisMutation of Vav1 adaptor region reveals a new oncogenic activation.The C-terminal SH3 domain contributes to the intramolecular inhibition of Vav family proteins.GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development.Mechanism and function of Vav1 localisation in TCR signalling.
P2860
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P2860
Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation
description
2000 nî lūn-bûn
@nan
2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Structural basis for relief of ...... av by tyrosine phosphorylation
@ast
Structural basis for relief of ...... av by tyrosine phosphorylation
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Structural basis for relief of ...... av by tyrosine phosphorylation
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Structural basis for relief of ...... av by tyrosine phosphorylation
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Structural basis for relief of ...... av by tyrosine phosphorylation
@en
Structural basis for relief of ...... av by tyrosine phosphorylation
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Structural basis for relief of ...... av by tyrosine phosphorylation
@ast
Structural basis for relief of ...... av by tyrosine phosphorylation
@en
Structural basis for relief of ...... av by tyrosine phosphorylation
@nl
P2093
P3181
P1433
P1476
Structural basis for relief of ...... av by tyrosine phosphorylation
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P2093
P304
P3181
P356
10.1016/S0092-8674(00)00085-4
P407
P577
2000-09-01T00:00:00Z