Structures of DNA Polymerase β with Active-Site Mismatches Suggest a Transient Abasic Site Intermediate during Misincorporation
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DNA polymerase family X: function, structure, and cellular rolesBase excision repair and cancerOn the origin of life in the Zinc world. 2. Validation of the hypothesis on the photosynthesizing zinc sulfide edifices as cradles of life on Earthα,β-Difluoromethylene Deoxynucleoside 5′-Triphosphates: A Convenient Synthesis of Useful Probes for DNA Polymerase β Structure and FunctionDNA Polymerase Substrate Specificity: SIDE CHAIN MODULATION OF THE"A-RULE"Mutagenic conformation of 8-oxo-7,8-dihydro-2′-dGTP in the confines of a DNA polymerase active siteHuman DNA Polymerase Mutations Allowing Efficient Abasic Site BypassReplication infidelity via a mismatch with Watson–Crick geometryThe structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an "ajar" intermediate conformation in the nucleotide selection mechanism.Molecular Insights into DNA Polymerase Deterrents for Ribonucleotide InsertionStructures of dNTP Intermediate States during DNA Polymerase Active Site AssemblyThe Miscoding Potential of 5-Hydroxycytosine Arises Due to Template Instability in the Replicative Polymerase Active SiteDNA Mismatch Synthesis Complexes Provide Insights into Base Selectivity of a B Family DNA PolymeraseDNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesionBinary complex crystal structure of DNA polymerase reveals multiple conformations of the templating 8-oxoguanine lesionBidentate and tridentate metal-ion coordination states within ternary complexes of RB69 DNA polymeraseAmino Acid Templating Mechanisms in Selection of Nucleotides Opposite Abasic Sites by a Family A DNA PolymeraseObserving a DNA Polymerase Choose Right from WrongThe E295K Cancer Variant of Human Polymerase Favors the Mismatch Conformational Pathway during Nucleotide SelectionStructural Basis for Promutagenicity of 8-Halogenated GuanineSustained active site rigidity during synthesis by human DNA polymerase μMetal-Dependent Conformational Activation Explains Highly Promutagenic Replication across O6-Methylguanine by Human DNA Polymerase βTransition-state destabilization reveals how human DNA polymerase β proceeds across the chemically unstable lesion N7-methylguanineStructures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity MechanismStructure and mechanism of DNA polymerase βRevealing the role of the product metal in DNA polymerase β catalysis.Structural comparison of DNA polymerase architecture suggests a nucleotide gateway to the polymerase active site.Alpha,beta-methylene-2'-deoxynucleoside 5'-triphosphates as noncleavable substrates for DNA polymerases: isolation, characterization, and stability studies of novel 2'-deoxycyclonucleosides, 3,5'-cyclo-dG, and 2,5'-cyclo-dT.DNA polymerase beta ribonucleotide discrimination: insertion, misinsertion, extension, and coding.The spontaneous replication error and the mismatch discrimination mechanisms of human DNA polymerase βStructural basis for the inefficient nucleotide incorporation opposite cisplatin-DNA lesion by human DNA polymerase β.Substrate-induced DNA polymerase β activation.DNA polymerase structure-based insight on the mutagenic properties of 8-oxoguanine.DNA polymerases provide a canon of strategies for translesion synthesis past oxidatively generated lesions.Prechemistry versus preorganization in DNA replication fidelity.MsDpo4-a DinB Homolog from Mycobacterium smegmatis-Is an Error-Prone DNA Polymerase That Can Promote G:T and T:G Mismatches.Base excision repair and design of small molecule inhibitors of human DNA polymerase β.Metal-induced DNA translocation leads to DNA polymerase conformational activation.New structural snapshots provide molecular insights into the mechanism of high fidelity DNA synthesis.Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer
P2860
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P2860
Structures of DNA Polymerase β with Active-Site Mismatches Suggest a Transient Abasic Site Intermediate during Misincorporation
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structures of DNA Polymerase β ...... ediate during Misincorporation
@ast
Structures of DNA Polymerase β ...... ediate during Misincorporation
@en
Structures of DNA Polymerase β ...... ediate during Misincorporation
@nl
type
label
Structures of DNA Polymerase β ...... ediate during Misincorporation
@ast
Structures of DNA Polymerase β ...... ediate during Misincorporation
@en
Structures of DNA Polymerase β ...... ediate during Misincorporation
@nl
prefLabel
Structures of DNA Polymerase β ...... ediate during Misincorporation
@ast
Structures of DNA Polymerase β ...... ediate during Misincorporation
@en
Structures of DNA Polymerase β ...... ediate during Misincorporation
@nl
P2093
P2860
P1433
P1476
Structures of DNA polymerase b ...... ediate during misincorporation
@en
P2093
David D Shock
Vinod K Batra
William A Beard
P2860
P304
P356
10.1016/J.MOLCEL.2008.02.025
P577
2008-05-01T00:00:00Z